Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.
about
Cancer metabolism and oxidative stress: Insights into carcinogenesis and chemotherapy via the non-dihydrofolate reductase effects of methotrexateThe eIF2 kinase GCN2 is essential for the murine immune system to adapt to amino acid deprivation by asparaginaseCell-cycle inhibition by Helicobacter pylori L-asparaginaseInhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.The eukaryotic initiation factor 2 kinase GCN2 protects against hepatotoxicity during asparaginase treatment.Role of ion transport in control of apoptotic cell death.Drug-induced amino acid deprivation as strategy for cancer therapy.Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell linesGlutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts.Pharmacology, immunogenicity, and efficacy of a novel pegylated recombinant Erwinia chrysanthemi-derived L-asparaginase.Binding of nickel to testicular glutamate-ammonia ligase inhibits its enzymatic activity.Pharmacokinetic, pharmacodynamic and intracellular effects of PEG-asparaginase in newly diagnosed childhood acute lymphoblastic leukemia: results from a single agent window study.Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase.Glutamine stimulates mTORC1 independent of the cell content of essential amino acids.The non-proteinogenic amino acids L-methionine sulfoximine and DL-phosphinothricin activate mTOR.
P2860
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P2860
Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.
@en
Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.
@nl
type
label
Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.
@en
Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.
@nl
prefLabel
Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.
@en
Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.
@nl
P2093
P2860
P356
P1476
Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.
@en
P2093
Bianca Maria Rotoli
Gian C Gazzola
Guido Orlandini
Jacopo Uggeri
Rita Gatti
Rossana Visigalli
Valeria Dall'Asta
P2860
P304
P356
10.1159/000087238
P577
2005-01-01T00:00:00Z