The alpha-helical to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation.
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Interactions of AChE with Aβ Aggregates in Alzheimer's Brain: Therapeutic Relevance of IDN 5706Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assemblyInfluence of preformed Asp23-Lys28 salt bridge on the conformational fluctuations of monomers and dimers of Abeta peptides with implications for rates of fibril formationHalogenation generates effective modulators of amyloid-Beta aggregation and neurotoxicity.Aggregation of Aß(25-35) on DOPC and DOPC/DHA bilayers: an atomic force microscopy studyIntracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification.Comparison of the structures of beta amyloid peptide (25-35) and substance P in trifluoroethanol/water solution.Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme.Beta-D-glucoside utilization by Mycoplasma mycoides subsp. mycoides SC: possible involvement in the control of cytotoxicity towards bovine lung cells.Cytotoxic aggregation and amyloid formation by the myostatin precursor proteinStructural Changes of Amyloid Beta in Hippocampus of Rats Exposed to Ozone: A Raman Spectroscopy Study.Amyloid formation from an α-helix peptide bundle is seeded by 3(10)-helix aggregates.Simultaneous single-molecule fluorescence and conductivity studies reveal distinct classes of Abeta species on lipid bilayersTilted peptides: a motif for membrane destabilization (hypothesis).Conformational transition of amyloid beta-peptide.Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils.Anti-amyloidogenic and anti-apoptotic role of melatonin in Alzheimer diseaseThe length of amyloid-beta in hereditary cerebral hemorrhage with amyloidosis, Dutch type. Implications for the role of amyloid-beta 1-42 in Alzheimer's disease.Feasibility of β-sheet breaker peptide-H102 treatment for Alzheimer's disease based on β-amyloid hypothesis.Can misfolded proteins be beneficial? The HAMLET case.Immunological approaches as therapy for Alzheimer's disease.Nicotine attenuates beta-amyloid peptide-induced neurotoxicity, free radical and calcium accumulation in hippocampal neuronal cultures.Protein folding in the endoplasmic reticulum: lessons from the human chorionic gonadotropin beta subunitInhibition of the electrostatic interaction between beta-amyloid peptide and membranes prevents beta-amyloid-induced toxicity.Role of the familial Dutch mutation E22Q in the folding and aggregation of the 15-28 fragment of the Alzheimer amyloid-beta protein.Propagating structure of Alzheimer's beta-amyloid(10-35) is parallel beta-sheet with residues in exact registerAmyloid-cholinesterase interactions. Implications for Alzheimer's disease.Computational selection of inhibitors of Abeta aggregation and neuronal toxicity.Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids.Enhanced pathologic properties of Dutch-type mutant amyloid beta-protein.The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?A survey of peptides with effective therapeutic potential in Alzheimer's disease rodent models or in human clinical studies.The role of molecular simulations in the development of inhibitors of amyloid β-peptide aggregation for the treatment of Alzheimer's diseaseAnalytical methods and formulation factors to enhance protein stability in solution.Charge regulation phenomenon predicted from the modeling of polypeptide electrophoretic mobilities as a relevant mechanism of amyloid-beta peptide oligomerization.Impact of a discordant helix on β-amyloid structure, aggregation ability and toxicity.Inhibition of amyloid peptide fragment Aβ25-35 fibrillogenesis and toxicity by N-terminal β-amino acid-containing esapeptides: is taurine moiety essential for in vivo effects?Computational and experimental studies on β-sheet breakers targeting Aβ1-40 fibrils.Expression of scavenger receptors in glial cells. Comparing the adhesion of astrocytes and microglia from neonatal rats to surface-bound beta-amyloid.The toxicity in vitro of beta-amyloid protein.
P2860
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P2860
The alpha-helical to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh-hant
name
The alpha-helical to beta-stra ...... e modulates amyloid formation.
@en
The alpha-helical to beta-stra ...... e modulates amyloid formation.
@nl
type
label
The alpha-helical to beta-stra ...... e modulates amyloid formation.
@en
The alpha-helical to beta-stra ...... e modulates amyloid formation.
@nl
prefLabel
The alpha-helical to beta-stra ...... e modulates amyloid formation.
@en
The alpha-helical to beta-stra ...... e modulates amyloid formation.
@nl
P2093
P2860
P356
P1476
The alpha-helical to beta-stra ...... e modulates amyloid formation.
@en
P2093
Castaño EM
Frangione B
Inestrosa NC
P2860
P304
P356
10.1074/JBC.270.7.3063
P407
P577
1995-02-01T00:00:00Z