Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy.
about
Endoreplication: polyploidy with purposeAberrant regulation of FBW7 in cancer.Role of Pirh2 in mediating the regulation of p53 and c-Myc.Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancerp53: guardian of ploidyIllicit survival of cancer cells during polyploidization and depolyploidization.Emerging roles of the FBW7 tumour suppressor in stem cell differentiation.Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas.The two faces of FBW7 in cancer drug resistance.FBXW7 negatively regulates ENO1 expression and function in colorectal cancer.Tumor suppressor functions of FBW7 in cancer development and progression.Selective killing of p53-deficient cancer cells by SP600125.Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint.The ubiquitous nature of cancer: the role of the SCF(Fbw7) complex in development and transformationStudy of single nucleotide polymorphisms of FBW7 and its substrate genes revealed a predictive factor for paclitaxel plus cisplatin chemotherapy in Chinese patients with advanced esophageal squamous cell carcinoma.MicroRNA-32 promotes cell proliferation, migration and suppresses apoptosis in breast cancer cells by targeting FBXW7Recent advances in SCF ubiquitin ligase complex: Clinical implicationsRole of STAT3/5 and Bcl-2/xL in 2-methoxyestradiol-induced endoreduplication of nasopharyngeal carcinoma cells.Differential regulation of FBXW7 isoforms by various stress stimuli.Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer
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P2860
Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Fbw7 regulates the activity of ...... event drug-induced polyploidy.
@en
Fbw7 regulates the activity of ...... event drug-induced polyploidy.
@nl
type
label
Fbw7 regulates the activity of ...... event drug-induced polyploidy.
@en
Fbw7 regulates the activity of ...... event drug-induced polyploidy.
@nl
prefLabel
Fbw7 regulates the activity of ...... event drug-induced polyploidy.
@en
Fbw7 regulates the activity of ...... event drug-induced polyploidy.
@nl
P2093
P2860
P356
P1433
P1476
Fbw7 regulates the activity of ...... revent drug-induced polyploidy
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2008.77
P407
P50
P577
2008-04-07T00:00:00Z