Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
about
FBXW7-mediated degradation of CCDC6 is impaired by ATM during DNA damage response in lung cancer cellsLow-molecular-weight cyclin E: the missing link between biology and clinical outcomePredisposition to cancer caused by genetic and functional defects of mammalian Atad5Practical issues in the diagnosis of serous carcinoma of the endometriumMutation analysis of hCDC4 in AML cells identifies a new intronic polymorphism.FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.Cyclin E involved in early stage carcinogenesis of esophageal adenocarcinoma by SNP DNA microarray and immunohistochemical studies.The genomics and genetics of endometrial cancer.Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genesCCNE1 amplification is associated with aggressive potential in endometrioid endometrial carcinomas.Targeted therapy in uterine serous carcinoma: an aggressive variant of endometrial cancer.FBW7 increases drug sensitivity to cisplatin in human nasopharyngeal carcinoma by downregulating the expression of multidrug resistance-associated protein.CRKL overexpression promotes cell proliferation and inhibits apoptosis in endometrial carcinoma.Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy.CCNE1 copy-number gain and overexpression identify ovarian clear cell carcinoma with a poor prognosis.Mutational and LOH analyses of the chromosome 4q region in esophageal adenocarcinoma.A study of the expression of Cyclin E and its isoforms in tumor and adjacent mucosa, correlated to patient outcome in early colon cancer.Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.Somatic mutation of hCDC4 gene is rare in lung adenocarcinomas.Comprehensive analysis of 19q12 amplicon in human gastric cancers.Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress.
P2860
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P2860
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
description
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Dezember 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: December 2003)
@en
vedecký článok (publikovaný 2003-12)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd in 2003-12)
@nl
наукова стаття, опублікована в грудні 2003
@uk
مقالة علمية (نشرت في ديسمبر 2003)
@ar
name
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
@ast
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
@en
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
@nl
type
label
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
@ast
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
@en
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
@nl
prefLabel
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
@ast
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
@en
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
@nl
P2093
P2860
P50
P356
P1476
Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma
@en
P2093
José Palacios
Juan C Cigudosa
Raúl Cassia
P2860
P304
P356
10.1002/PATH.1474
P407
P577
2003-12-01T00:00:00Z