Zinc and 4-hydroxy-2-nonenal mediate lysosomal membrane permeabilization induced by H2O2 in cultured hippocampal neurons.
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Modulation of neuronal signal transduction and memory formation by synaptic zincA fluorescent indicator for imaging lysosomal zinc(II) with Förster resonance energy transfer (FRET)-enhanced photostability and a narrow band of emission.Zn²⁺ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulationBiphasic regulation of lysosomal exocytosis by oxidative stressIntracellular accumulation dynamics and fate of zinc ions in alveolar epithelial cells exposed to airborne ZnO nanoparticles at the air-liquid interfaceThe Application of Curve Fitting on the Voltammograms of Various Isoforms of Metallothioneins-Metal Complexes.Pathophysiologically relevant levels of hydrogen peroxide induce glutamate-independent neurodegeneration that involves activation of transient receptor potential melastatin 7 channelsTissue plasminogen activator alters intracellular sequestration of zinc through interaction with the transporter ZIP4Zn2+ efflux through lysosomal exocytosis prevents Zn2+-induced toxicity.Fluorescent sensors for measuring metal ions in living systemsZn(II)-coordination modulated ligand photophysical processes - the development of fluorescent indicators for imaging biological Zn(II) ionsOxidative stress and autophagy in the regulation of lysosome-dependent neuron death.Pathological aspects of lipid peroxidation.Zinc bells rang in Jerusalem!Zinc dyshomeostasis is linked with the loss of mucolipidosis IV-associated TRPML1 ion channel.Roles of zinc and metallothionein-3 in oxidative stress-induced lysosomal dysfunction, cell death, and autophagy in neurons and astrocytes.Zinc in innate and adaptive tumor immunity.TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemiaDisparate roles of zinc in chemical hypoxia-induced neuronal death.ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution.The neurophysiology and pathology of brain zinc.The Role of Oxidized Cholesterol in Diabetes-Induced Lysosomal Dysfunction in the Brain.Neuroprotective effects of reactive oxygen species mediated by BDNF-independent activation of TrkB.AMP-activated protein kinase contributes to zinc-induced neuronal death via activation by LKB1 and induction of Bim in mouse cortical cultures.Naturally occurring variation in the Glutathione-S-Transferase 4 gene determines neurodegeneration after traumatic brain injury.Glucose Modulation Induces Lysosome Formation and Increases Lysosomotropic Drug Sequestration via the P-Glycoprotein Drug Transporter.Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+.A mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC.The interactive roles of zinc and calcium in mitochondrial dysfunction and neurodegeneration.Zinc homeostasis and signaling in glia.Lysosomal membrane permeabilization as a key player in brain ischemic cell death: a "lysosomocentric" hypothesis for ischemic brain damage.The biology of zinc transport in mammary epithelial cells: implications for mammary gland development, lactation, and involution.The role of intracellular zinc release in aging, oxidative stress, and Alzheimer's disease.Organelle-specific initiation of cell death.Photoluminescence imaging of Zn(2+) in living systems.A conditional proteomics approach to identify proteins involved in zinc homeostasis.TNFα Post-Translationally Targets ZnT2 to Accumulate Zinc in Lysosomes.The mucolipin-1 (TRPML1) ion channel, transmembrane-163 (TMEM163) protein, and lysosomal zinc handling.Direct comparison of a genetically encoded sensor and small molecule indicator: implications for quantification of cytosolic Zn(2+).Cellular zinc levels are modulated by TRPML1-TMEM163 interaction.
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P2860
Zinc and 4-hydroxy-2-nonenal mediate lysosomal membrane permeabilization induced by H2O2 in cultured hippocampal neurons.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Zinc and 4-hydroxy-2-nonenal m ...... cultured hippocampal neurons.
@en
Zinc and 4-hydroxy-2-nonenal m ...... cultured hippocampal neurons.
@nl
type
label
Zinc and 4-hydroxy-2-nonenal m ...... cultured hippocampal neurons.
@en
Zinc and 4-hydroxy-2-nonenal m ...... cultured hippocampal neurons.
@nl
prefLabel
Zinc and 4-hydroxy-2-nonenal m ...... cultured hippocampal neurons.
@en
Zinc and 4-hydroxy-2-nonenal m ...... cultured hippocampal neurons.
@nl
P2093
P1476
Zinc and 4-hydroxy-2-nonenal m ...... n cultured hippocampal neurons
@en
P2093
Jae-Hyung Cho
Jae-Young Koh
Jung Jin Hwang
Sook-Jeong Lee
Tae-Youn Kim
P304
P356
10.1523/JNEUROSCI.0199-08.2008
P407
P577
2008-03-01T00:00:00Z