Neuroprotective effects of tempol, a catalytic scavenger of peroxynitrite-derived free radicals, in a mouse traumatic brain injury model. - Wikidata - awgldk - TriplyDB

Neuroprotective effects of tempol, a catalytic scavenger of peroxynitrite-derived free radicals, in a mouse traumatic brain injury model.

Neuroprotective effects of tempol, a catalytic scavenger of peroxynitrite-derived free radicals, in a mouse traumatic brain injury model.

http://www.wikidata.org/entity/Q46718842

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Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury Effects of tempol and redox-cycling nitroxides in models of oxidative stress.Therapeutic window analysis of the neuroprotective effects of cyclosporine A after traumatic brain injury Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke Traumatic brain injury and NADPH oxidase: a deep relationship Protective Effect of Tempol against Cisplatin-Induced Ototoxicity.What's New in Traumatic Brain Injury: Update on Tracking, Monitoring and Treatment Antioxidant therapies for traumatic brain injury.Loss of TRPM2 function protects against irradiation-induced salivary gland dysfunction Resuscitation of traumatic brain injury and hemorrhagic shock with polynitroxylated albumin, hextend, hypertonic saline, and lactated Ringer's: Effects on acute hemodynamics, survival, and neuronal death in mice.Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury.Antioxidant therapies in traumatic brain and spinal cord injury Lipid peroxidation-derived reactive aldehydes directly and differentially impair spinal cord and brain mitochondrial function.Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation.Axonal pathology in traumatic brain injury.Location and level of Etk expression in neurons are associated with varied severity of traumatic brain injury A pharmacological analysis of the neuroprotective efficacy of the brain- and cell-permeable calpain inhibitor MDL-28170 in the mouse controlled cortical impact traumatic brain injury model.Mitochondrial protection after traumatic brain injury by scavenging lipid peroxyl radicals.Pharmacological inhibition of lipid peroxidation attenuates calpain-mediated cytoskeletal degradation after traumatic brain injury.Nrf2-ARE activator carnosic acid decreases mitochondrial dysfunction, oxidative damage and neuronal cytoskeletal degradation following traumatic brain injury in mice.The combination of either tempol or FK506 with delayed hypothermia: implications for traumatically induced microvascular and axonal protection S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats.Post-injury administration of the mitochondrial permeability transition pore inhibitor, NIM811, is neuroprotective and improves cognition after traumatic brain injury in rats P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite Administration of COG1410 reduces axonal amyloid precursor protein immunoreactivity and microglial activation after controlled cortical impact in mice.Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI.Relationship of nitric oxide synthase induction to peroxynitrite-mediated oxidative damage during the first week after experimental traumatic brain injury Analysis of regional brain mitochondrial bioenergetics and susceptibility to mitochondrial inhibition utilizing a microplate based system Phenelzine mitochondrial functional preservation and neuroprotection after traumatic brain injury related to scavenging of the lipid peroxidation-derived aldehyde 4-hydroxy-2-nonenal.Therapy development for diffuse axonal injury.Antioxidant Treatment Limits Neuroinflammation in Experimental Glaucoma.Tempol protects blood proteins and lipids against peroxynitrite-mediated oxidative damage.Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion.Pharmacological evidence for a role of peroxynitrite in the pathophysiology of spinal cord injury.Tempol protection of spinal cord mitochondria from peroxynitrite-induced oxidative damage.Drug targets for traumatic brain injury from poly(ADP-ribose)polymerase pathway modulation.Evidence for the therapeutic efficacy of either mild hypothermia or oxygen radical scavengers after repetitive mild traumatic brain injury.Calpain as a therapeutic target in traumatic brain injury.Novel therapeutic strategies for traumatic brain injury: acute antioxidant reinforcement.

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P2860

Neuroprotective effects of tempol, a catalytic scavenger of peroxynitrite-derived free radicals, in a mouse traumatic brain injury model.

http://www.wikidata.org/entity/Q46718842

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年學術文章

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Neuroprotective effects of tem ...... traumatic brain injury model.

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Neuroprotective effects of tem ...... traumatic brain injury model.

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Neuroprotective effects of tem ...... traumatic brain injury model.

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Neuroprotective effects of tem ...... traumatic brain injury model.

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Edward D Hall

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Indrapal N Singh

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Kimberly M Carrico

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Ying Deng-Bryant

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P2860

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase.

Calpain and caspase: can you tell the difference?

Application of silver degeneration stains for neurotoxicity testing.

Oxidative damage and mitochondrial decay in aging.

Characterization and function of mitochondrial nitric-oxide synthase.

A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling.

Cytoskeletal protein degradation and neurodegeneration evolves differently in males and females following experimental head injury.

Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury.

Antioxidant Tempol enhances hypothermic cerebral preservation during prolonged cardiac arrest in dogs.

Generation of reactive oxygen species by the mitochondrial electron transport chain.

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1114-1126

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10.1038/JCBFM.2008.10

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