about
Recent advances in understanding apicomplexan parasitesDiversity of CRISPR-Cas immune systems and molecular machinesSingle-Base Pair Genome Editing in Human Cells by Using Site-Specific EndonucleasesEngineering large animal models of human diseaseUse of designer nucleases for targeted gene and genome editing in plantsSynthetic biology and occupational risk2015 Clinical trials update in sickle cell anemiaThe evolutionary ecology of molecular replicatorsPrevention of Preharvest Sprouting through Hormone Engineering and Germination Recovery by Chemical BiologyAdvancements in zebrafish applications for 21st century toxicology.Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research.Human Germline CRISPR-Cas Modification: Toward a Regulatory Framework.Applications of CRISPR technologies in research and beyond.Planted forest health: The need for a global strategy.No time to waste--the ethical challenges created by CRISPR: CRISPR/Cas, being an efficient, simple, and cheap technology to edit the genome of any organism, raises many ethical and regulatory issues beyond the use to manipulate human germ line cellsDNA-binding-domain fusions enhance the targeting range and precision of Cas9.GUIDEseq: a bioconductor package to analyze GUIDE-Seq datasets for CRISPR-Cas nucleases.Synthetic dual-input mammalian genetic circuits enable tunable and stringent transcription control by chemical and light.Comparison of CRISPR/Cas9 and TALENs on editing an integrated EGFP gene in the genome of HEK293FT cellsTechnological advances in precision medicine and drug development.The Challenges and Opportunities Associated with Biofortification of Pearl Millet (Pennisetum glaucum) with Elevated Levels of Grain Iron and Zinc.Programmable Genome Editing Tools and their Regulation for Efficient Genome Engineering.The anti-melanoma activity and oncogenic targets of hsa-miR-15a-5pMitochondrial Modification Techniques and Ethical Issues.CRISPR-Based Technologies and the Future of Food Science.Proteomics in the genome engineering era.From hacking the human genome to editing organsCreating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.Saving orphan drug legislations: misconceptions and clarifications."I bet you won't": The science-society wager on gene editing techniques.A functional screening of the kinome identifies the Polo-like kinase 4 as a potential therapeutic target for malignant rhabdoid tumors, and possibly, other embryonal tumors of the brain.Viral vector-based tools advance knowledge of basal ganglia anatomy and physiology.Ethical issues of CRISPR technology and gene editing through the lens of solidarity.CRISPR: taking the shortcut to a healthy genome editing enterprise.Canadian regulatory perspectives on genome engineered crops.CRISPR as a driving force: the Model T of biotechnology.Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM).CRISPR and the Rebirth of Synthetic Biology.The genome editing revolution: A CRISPR-Cas TALE off-target story.Somatic Engineering of Oncogenic Chromosomal Rearrangements: A Perspective
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh-hant
name
CRISPR, the disruptor.
@en
CRISPR, the disruptor.
@nl
type
label
CRISPR, the disruptor.
@en
CRISPR, the disruptor.
@nl
prefLabel
CRISPR, the disruptor.
@en
CRISPR, the disruptor.
@nl
P356
P1433
P1476
CRISPR, the disruptor.
@en
P2888
P356
10.1038/522020A
P407
P577
2015-06-01T00:00:00Z
P5875
P6179
1005511289