Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice.
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Alzheimer's disease as homeostatic responses to age-related myelin breakdownThe cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor proteinImpact of apolipoprotein E on Alzheimer's diseaseLipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseApoE promotes the proteolytic degradation of AbetaApolipoprotein E: from cardiovascular disease to neurodegenerative disordersApolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer diseaseThe liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein ECyclodextrins as Emerging Therapeutic Tools in the Treatment of Cholesterol-Associated Vascular and Neurodegenerative DiseasesDefensive effect of lansoprazole in dementia of AD type in mice exposed to streptozotocin and cholesterol enriched dietIdentification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in AstrocytesOverexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearanceRole of Abca7 in mouse behaviours relevant to neurodegenerative diseases.ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice.Alzheimer disease models and human neuropathology: similarities and differencesEffect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trialOpposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice.Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscleMetals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice.LCAT deficiency does not impair amyloid metabolism in APP/PS1 miceCerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in miceApolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 miceAmyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo.Apolipoprotein E: from lipid transport to neurobiologyModulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injuryThe role of apolipoprotein E in Alzheimer's disease.MicroRNAs: a connection between cholesterol metabolism and neurodegeneration.HDL and cognition in neurodegenerative disorders.Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases.ABCA8 stimulates sphingomyelin production in oligodendrocytes.Juvenile traumatic brain injury induces long-term perivascular matrix changes alongside amyloid-beta accumulation.Domains of apoE4 required for the biogenesis of apoE-containing HDL.Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculatureImprovement of memory deficits and amyloid-β clearance in aged APP23 mice treated with a combination of anti-amyloid-β antibody and LXR agonistAn ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia.Nuclear receptors as therapeutic targets for Alzheimer's diseaseAnalysis of differential secondary effects of novel rexinoids: select rexinoid X receptor ligands demonstrate differentiated side effect profiles.Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels.
P2860
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P2860
Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Lack of ABCA1 considerably dec ...... loid deposition in APP23 mice.
@en
Lack of ABCA1 considerably dec ...... loid deposition in APP23 mice.
@nl
type
label
Lack of ABCA1 considerably dec ...... loid deposition in APP23 mice.
@en
Lack of ABCA1 considerably dec ...... loid deposition in APP23 mice.
@nl
prefLabel
Lack of ABCA1 considerably dec ...... loid deposition in APP23 mice.
@en
Lack of ABCA1 considerably dec ...... loid deposition in APP23 mice.
@nl
P2860
P356
P1476
Lack of ABCA1 considerably dec ...... loid deposition in APP23 mice.
@en
P2093
Iliya Lefterov
P2860
P304
43224-43235
P356
10.1074/JBC.M504513200
P407
P577
2005-10-05T00:00:00Z