Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection.
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Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.Motif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulationExamination of the expanding pathways for the regulation of p21 expression and activity.PP2Cgamma-mediated S-phase accumulation induced by the proteasome-dependent degradation of p21(WAF1/CIP1)Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localizationCDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiationA novel, non-apoptotic role for Scythe/BAT3: a functional switch between the pro- and anti-proliferative roles of p21 during the cell cycleThe ability of TRIM3 to induce growth arrest depends on RING-dependent E3 ligase activityp21 in cancer: intricate networks and multiple activitiesParkin Knockout Inhibits Neuronal Development via Regulation of Proteasomal Degradation of p21.Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states.Cullin-4A·DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis.Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligaseIdentification of Novel Proteasome Inhibitors from an Enaminone Library.Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitorsGrowth inhibition by miR-519 via multiple p21-inducing pathways.Inactivation of Cyclin E:Cdk2 complexes by p27/p21Ubiquitination of substrates by esterification.Less understood issues: p21(Cip1) in mitosis and its therapeutic potential.Transcriptomic and proteomic analyses in bone tumor cells: Deciphering parathyroid hormone-related protein regulation of the cell cycle and apoptosis.Hdm2- and proteasome-dependent turnover limits p21 accumulation during S phaseNUB1, an interferon-inducible protein, mediates anti-proliferative actions and apoptosis in renal cell carcinoma cells through cell-cycle regulation.Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaksp53- and p21-dependent premature APC/C-Cdh1 activation in G2 is part of the long-term response to genotoxic stress.Ionizing radiation induces ATM-independent degradation of p21Cip1 in transformed cells.Degradation of p21Cip1 through anaphase-promoting complex/cyclosome and its activator Cdc20 (APC/CCdc20) ubiquitin ligase complex-mediated ubiquitylation is inhibited by cyclin-dependent kinase 2 in cardiomyocytes.MDMX promotes proteasomal turnover of p21 at G1 and early S phases independently of, but in cooperation with, MDM2.APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase.Damaged-DNA Binding Protein-2 Drives Apoptosis Following DNA Damage.Targeting p21 degradation locally.The serine protease inhibitor serpinB2 binds and stabilizes p21 in senescent cells.Deubiquitylation and stabilization of p21 by USP11 is critical for cell-cycle progression and DNA damage responses.Whole-transcriptomic Profile of SK-MEL-3 Melanoma Cells Treated with the Histone Deacetylase Inhibitor: Trichostatin A
P2860
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P2860
Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Ubiquitination of p21Cip1/WAF1 ...... ubiquitination site selection.
@en
Ubiquitination of p21Cip1/WAF1 ...... ubiquitination site selection.
@nl
type
label
Ubiquitination of p21Cip1/WAF1 ...... ubiquitination site selection.
@en
Ubiquitination of p21Cip1/WAF1 ...... ubiquitination site selection.
@nl
prefLabel
Ubiquitination of p21Cip1/WAF1 ...... ubiquitination site selection.
@en
Ubiquitination of p21Cip1/WAF1 ...... ubiquitination site selection.
@nl
P2093
P356
P1433
P1476
Ubiquitination of p21Cip1/WAF1 ...... ubiquitination site selection
@en
P2093
Lucas Nacusi
Robert J Sheaff
P304
14553-14564
P356
10.1021/BI051071J
P407
P50
P577
2005-11-01T00:00:00Z