Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase.
about
Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand bindingThe Structure of Clostridium perfringens NanI Sialidase and Its Catalytic IntermediatesStructure of the catalytic domain ofStreptococcus pneumoniaesialidase NanAStructural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B VirusesStructural and Kinetic Analysis of Bacillus subtilis N-Acetylglucosaminidase Reveals a Unique Asp-His Dyad MechanismThe Aspergillus fumigatus Sialidase Is a 3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid Hydrolase (KDNase): STRUCTURAL AND MECHANISTIC INSIGHTSFunctional and Structural Analysis of Influenza Virus Neuraminidase N3 Offers Further Insight into the Mechanisms of Oseltamivir ResistanceInfluenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitorsMechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activityMechanistic study of CMP-Neu5Ac hydrolysis by α2,3-sialyltransferase from Pasteurella dagmatis.Unraveling the differences of the hydrolytic activity of Trypanosoma cruzi trans-sialidase and Trypanosoma rangeli sialidase: a quantum mechanics-molecular mechanics modeling study.The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design.Genetic and functional characterization of the NanA sialidase from Clostridium chauvoei.Sialic acid: a sweet swing between mammalian host and Trypanosoma cruziThe chemistry and biology of trypanosomal trans-sialidases: virulence factors in Chagas disease and sleeping sickness.Influenza virus neuraminidase: structure and function.Bacteriophage polysaccharide depolymerases and biomedical applications.Mechanistic investigations of unsaturated glucuronyl hydrolase from Clostridium perfringens.A sialosyl sulfonate as a potent inhibitor of influenza virus replication.Use of Fluorinated Functionality in Enzyme Inhibitor Development: Mechanistic and Analytical AdvantagesStreptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.Evidence of ternary complex formation in Trypanosoma cruzi trans-sialidase catalysisModulation of catalytic function by differential plasticity of the active site: case study of Trypanosoma cruzi trans-sialidase and Trypanosoma rangeli sialidase.Solid phase assay for comparing reactivation rates of neuraminidases of influenza wild type and resistant mutants after inhibitor removal.Procyclic Trypanosoma brucei expresses separate sialidase and trans-sialidase enzymes on its surface membrane.
P2860
Q27644222-7448B6B7-B135-4662-A1E7-97121539FFCAQ27649703-DCABB29D-6CE6-470C-B654-D10C6F98D1E6Q27651923-36FDE41C-D67E-4E51-BA60-F5B777488635Q27663966-B0891889-AE9F-4C09-962C-EAA7A777B15AQ27664387-B5E18735-9C40-4804-8871-8DC83CBCAEE1Q27666631-C6D3F186-0744-4436-AE23-4EFD41EBFC5BQ27678914-5354BF75-F11A-457D-B539-3015E24F1752Q27684045-6BDF2F9C-8A07-4A5D-8241-3A7C4A0F71DBQ27684054-E063BFB0-AB38-49A5-905C-C0A484C7EB5EQ30832222-06B1ED5C-CC75-496B-AE24-FFA868D13022Q33732570-3CFA16A9-55F1-4692-871A-C539D305A9F5Q33867041-96FD250C-8228-40D9-AFCC-B92D4F597C96Q34540938-4BDF7806-5EB0-4FE9-888C-2F6658CFF5D1Q36449555-A5CE1AAF-C37D-4274-920C-53679EB0CAF9Q37940361-B88C026A-2306-40E3-B764-60BA433D5D79Q38014839-CDB7797C-04AA-41AB-8515-B00D9BF39DCAQ38172443-E537F21A-D559-448D-98C7-B838CB45F9FBQ39998138-48D5A369-C530-4C94-BF18-7DC4474A00AAQ40186997-A11C0CD5-9D40-4089-8B0C-AA13BC2C393EQ41095327-5464E49F-8E4E-4995-AB52-7258ABDA360FQ41812892-765F9B1C-1286-4636-80ED-6B9095910118Q41848404-813D5C4B-36B1-4D12-B09F-F125A56CA19BQ41886449-63A33999-5945-421F-B956-EE17B62BD350Q42116998-E6380812-D7F1-4E1E-BFD8-BA08708B7626Q48084871-21156810-3BE3-4A19-AC3E-4D90A5253546
P2860
Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Structural and kinetic analysi ...... Trypanosoma rangeli sialidase.
@en
Structural and kinetic analysi ...... Trypanosoma rangeli sialidase.
@nl
type
label
Structural and kinetic analysi ...... Trypanosoma rangeli sialidase.
@en
Structural and kinetic analysi ...... Trypanosoma rangeli sialidase.
@nl
prefLabel
Structural and kinetic analysi ...... Trypanosoma rangeli sialidase.
@en
Structural and kinetic analysi ...... Trypanosoma rangeli sialidase.
@nl
P50
P356
P1476
Structural and kinetic analysi ...... Trypanosoma rangeli sialidase.
@en
P2093
Stephen G Withers
P304
P356
10.1074/JBC.M510677200
P407
P577
2005-11-18T00:00:00Z