Functional reconstruction and synthetic mimicry of a conformational epitope using CLIPS technology.
about
Structural and molecular basis for Ebola virus neutralization by protective human antibodiesStructural characterization of a novel Chlamydia pneumoniae type III secretion-associated protein, Cpn0803Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy.A combinatorial approach for the design of complementarity-determining region-derived peptidomimetics with in vitro anti-tumoral activity.Reverse epitope mapping of the E2 glycoprotein in antibody associated hepatitis C virus.Epitope mapping and key amino acid identification of anti-CD22 immunotoxin CAT-8015 using hybrid β-lactamase displayConservation of inter-protein binding sites in RUSH and RFBP, an ATP11B isoform.Requirements for empirical immunogenicity trials, rather than structure-based design, for developing an effective HIV vaccine.Therapeutic antibodies directed at G protein-coupled receptorsRapid identification of novel immunodominant proteins and characterization of a specific linear epitope of Campylobacter jejuni.Identification and mapping of linear antibody epitopes in human serum albumin using high-density Peptide arrays.A combination of in vitro techniques for efficient discovery of functional monoclonal antibodies against human CXC chemokine receptor-2 (CXCR2)Phage display and hybridoma generation of antibodies to human CXCR2 yields antibodies with distinct mechanisms and epitopes.Epitope Specificity Determines Pathogenicity and Detectability of Anti-Platelet-Derived Growth Factor Receptor α Autoantibodies in Systemic Sclerosis.Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in FrizzledBridged Analogues for p53-Dependent Cancer Therapy Obtained by S-AlkylationPemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface.Characterization of the complex formed between a potent neutralizing ovine-derived polyclonal anti-TNFα Fab fragment and human TNFα.The sclerostin-neutralizing antibody AbD09097 recognizes an epitope adjacent to sclerostin's binding site for the Wnt co-receptor LRP6Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity.Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1.Multiplexed screening of natural humoral immunity identifies antibodies at fine specificity for complex and dynamic viral targetsChlamydia Pneumoniae CdsL Regulates CdsN ATPase Activity, and Disruption with a Peptide Mimetic Prevents Bacterial Invasion.Reproductive component vaccine developments for contraceptive and non-contraceptive uses.Limitations to the structure-based design of HIV-1 vaccine immunogens.Peptides for immunological purposes: design, strategies and applications.Current approaches to fine mapping of antigen-antibody interactions.Specificity, polyspecificity, and heterospecificity of antibody-antigen recognition.Differential epitope recognition in the immunodominant staphylococcal antigen A of Staphylococcus aureus by mouse versus human IgG antibodies.Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis.Identification and fine mapping of a linear B cell epitope of human vimentin.Epitope mapping of Ebola virus dominant and subdominant glycoprotein epitopes facilitates construction of an epitope-based DNA vaccine able to focus the antibody response in mice.An analysis of B-cell epitope discontinuity.Reconstructing the discontinuous and conformational β1/β3-loop binding site on hFSH/hCG by using highly constrained multicyclic peptides.Cross-neutralization of four paramyxoviruses by a human monoclonal antibody.Generation and preclinical characterization of an antibody specific for SEMA4D.Peptide mimetics of immunoglobulin A (IgA) and FcαRI block IgA-induced human neutrophil activation and migration.Small cyclic agonists of iron regulatory hormone hepcidin.Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa.Application of Thiol-yne/Thiol-ene Reactions for Peptide and Protein Macrocyclizations.
P2860
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P2860
Functional reconstruction and synthetic mimicry of a conformational epitope using CLIPS technology.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Functional reconstruction and ...... pitope using CLIPS technology.
@en
Functional reconstruction and ...... pitope using CLIPS technology.
@nl
type
label
Functional reconstruction and ...... pitope using CLIPS technology.
@en
Functional reconstruction and ...... pitope using CLIPS technology.
@nl
prefLabel
Functional reconstruction and ...... pitope using CLIPS technology.
@en
Functional reconstruction and ...... pitope using CLIPS technology.
@nl
P2093
P2860
P356
P1476
Functional reconstruction and ...... pitope using CLIPS technology.
@en
P2093
Peter Timmerman
Rob H Meloen
Wouter C Puijk
P2860
P304
P356
10.1002/JMR.846
P577
2007-09-01T00:00:00Z