Ca2+-dependent generation of mitochondrial reactive oxygen species serves as a signal for poly(ADP-ribose) polymerase-1 activation during glutamate excitotoxicity.
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Programmed cellular necrosis mediated by the pore-forming alpha-toxin from Clostridium septicumMultiple sclerosis: molecular mechanisms and therapeutic opportunitiesPARP-1 expression is increased in colon adenoma and carcinoma and correlates with OGG1Silencing of human phosphatidylethanolamine-binding protein 4 enhances rituximab-induced death and chemosensitization in B-cell lymphomaDifferential NMDA receptor-dependent calcium loading and mitochondrial dysfunction in CA1 vs. CA3 hippocampal neuronsReactive oxygen species regulate F-actin dynamics in neuronal growth cones and neurite outgrowth.Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDsDifferential role of poly(ADP-ribose) polymerase in D. discoideum growth and development.Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture.MCP-1-activated monocytes induce apoptosis in human retinal pigment epithelium.Mitochondria and arrhythmias.Mitochondrial ion channels/transporters as sensors and regulators of cellular redox signaling.Reactive oxygen species are involved in group I mGluR-mediated facilitation of nociceptive processing in amygdala neurons.Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1.Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.NADPH oxidase-2: linking glucose, acidosis, and excitotoxicity in stroke.Oxidative stress-mediated regulation of proteasome complexesMitochondrial Ca(2+) uptake is essential for synaptic plasticity in pain.Selective dendritic susceptibility to bioenergetic, excitotoxic and redox perturbations in cortical neurons.Transient mitochondrial permeability transition mediates excitotoxicity in glutamate-sensitive NSC34D motor neuron-like cellsGenetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release.Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart FailureMacrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE-/- mice on a Western dTherapeutic applications of PARP inhibitors: anticancer therapy and beyondPINK1 and Parkin cooperatively protect neurons against constitutively active TRP channel-induced retinal degeneration in Drosophila.Mitochondria, oxidative stress and PARP-1 network: a new target for neuroprotective effects of tetracyclines?Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicityCalcium dysregulation induces apoptosis-inducing factor release: cross-talk between PARP-1- and calpain-signaling pathways.The pathophysiology of traumatic brain injury at a glance.NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation.Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding.Oxysterols in heart failure.The interactive roles of zinc and calcium in mitochondrial dysfunction and neurodegeneration.Mitochondrial ryanodine receptors and other mitochondrial Ca2+ permeable channels.PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegenerationMitochondria, calcium-dependent neuronal death and neurodegenerative disease.Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases.Activation of PARP by oxidative stress induced by β-amyloid: implications for Alzheimer's disease.Pannexin1 as a novel cerebral target in pathogenesis of hepatic encephalopathy.Neuroprotective Mechanisms of Taurine against Ischemic Stroke.
P2860
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P2860
Ca2+-dependent generation of mitochondrial reactive oxygen species serves as a signal for poly(ADP-ribose) polymerase-1 activation during glutamate excitotoxicity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Ca2+-dependent generation of m ...... es serves as a signal for poly
@nl
Ca2+-dependent generation of m ...... ring glutamate excitotoxicity.
@en
type
label
Ca2+-dependent generation of m ...... es serves as a signal for poly
@nl
Ca2+-dependent generation of m ...... ring glutamate excitotoxicity.
@en
prefLabel
Ca2+-dependent generation of m ...... es serves as a signal for poly
@nl
Ca2+-dependent generation of m ...... ring glutamate excitotoxicity.
@en
P2093
P2860
P1476
Ca2+-dependent generation of m ...... ring glutamate excitotoxicity.
@en
P2093
Robert A Gross
Shey-Shing Sheu
Yuntao Duan
P2860
P304
P356
10.1113/JPHYSIOL.2007.145409
P407
P577
2007-10-18T00:00:00Z