Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5.
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The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathwaysRING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer geneThe tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma.The COP9 signalosome regulates Skp2 levels and proliferation of human cells.Cop9 signalosome subunit 8 (CSN8) is essential for Drosophila development.
P2860
Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5.
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Growth suppression induced by ...... e is dependent upon JAB1/CSN5.
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Growth suppression induced by ...... e is dependent upon JAB1/CSN5.
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Growth suppression induced by ...... e is dependent upon JAB1/CSN5.
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Growth suppression induced by ...... e is dependent upon JAB1/CSN5.
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Growth suppression induced by ...... e is dependent upon JAB1/CSN5.
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Growth suppression induced by ...... e is dependent upon JAB1/CSN5.
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P2093
P2860
P356
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Growth suppression induced by ...... e is dependent upon JAB1/CSN5.
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P2093
Daniel Segal
Harry A Drabkin
Jason P Lee
Joan E Hooper
Robert M Gemmill
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P2888
P304
P356
10.1038/SJ.ONC.1208509
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P577
2005-05-01T00:00:00Z