Structural determinants for high-affinity binding in a Nedd4 WW3* domain-Comm PY motif complex.
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Role of the UPS in Liddle syndromeNedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and functionStructural basis for polyproline recognition by the FE65 WW domainStructural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β PathwaysThe ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localizationNedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functionsProline-rich Gla protein 2 is a cell-surface vitamin K-dependent protein that binds to the transcriptional coactivator Yes-associated proteinSolution structure of an atypical WW domain in a novel beta-clam-like dimeric formSpecificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of DeltexStructural and Biochemical Basis for Ubiquitin Ligase Recruitment by Arrestin-related Domain-containing Protein-3 (ARRDC3)An expanded WW domain recognition motif revealed by the interaction between Smad7 and the E3 ubiquitin ligase Smurf2Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligasesComparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arraysThe inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4E3 ubiquitin-protein ligases in rat kidney collecting duct: response to vasopressin stimulation and withdrawalUbiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast.Nedd4-2-mediated ubiquitination facilitates processing of surfactant protein-CLys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein.A splice isoform of DNedd4, DNedd4-long, negatively regulates neuromuscular synaptogenesis and viability in Drosophila.Commissureless regulation of axon outgrowth across the midline is independent of Rab function.Versatile roles of k63-linked ubiquitin chains in trafficking.Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling.The E3 ubiquitin ligase SMAD ubiquitination regulatory factor 2 negatively regulates Krüppel-like factor 5 protein.Alternatively spliced proline-rich cassettes link WNK1 to aldosterone actionNo exit: targeting the budding process to inhibit filovirus replication.The role of the ubiquitin-proteasome system in kidney diseases.U24 from Roseolovirus interacts strongly with Nedd4 WW Domains.An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network.Multiple interactions drive adaptor-mediated recruitment of the ubiquitin ligase rsp5 to membrane proteins in vivo and in vitro.Bul proteins, a nonredundant, antagonistic family of ubiquitin ligase regulatory proteins.Multiple WW domains of Nedd4-1 undergo conformational exchange that is quenched upon peptide binding.Regulation of Commissureless by the ubiquitin ligase DNedd4 is required for neuromuscular synaptogenesis in Drosophila melanogasterSeptin 4, the drosophila ortholog of human CDCrel-1, accumulates in parkin mutant brains and is functionally related to the Nedd4 E3 ubiquitin ligase.NEDD4-1 protects against ischaemia/reperfusion-induced cardiomyocyte apoptosis via the PI3K/Akt pathway.Intestinal knockout of Nedd4 enhances growth of Apcmin tumors.Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity.
P2860
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P2860
Structural determinants for high-affinity binding in a Nedd4 WW3* domain-Comm PY motif complex.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Structural determinants for hi ...... domain-Comm PY motif complex.
@en
Structural determinants for hi ...... domain-Comm PY motif complex.
@nl
type
label
Structural determinants for hi ...... domain-Comm PY motif complex.
@en
Structural determinants for hi ...... domain-Comm PY motif complex.
@nl
prefLabel
Structural determinants for hi ...... domain-Comm PY motif complex.
@en
Structural determinants for hi ...... domain-Comm PY motif complex.
@nl
P2093
P1433
P1476
Structural determinants for hi ...... domain-Comm PY motif complex.
@en
P2093
Daniela Rotin
M Christine Bruce
Voula Kanelis
P304
P356
10.1016/J.STR.2005.11.018
P577
2006-03-01T00:00:00Z