Melatonin prevents ultraviolet radiation-induced alterations in plasma membrane potential and intracellular pH in human keratinocytes.

Melatonin prevents ultraviolet radiation-induced alterations in plasma membrane potential and intracellular pH in human keratinocytes.

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http://www.wikidata.org/entity/Q47310855
Local melatoninergic system as the protector of skin integrityMelatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.N1-Acetyl-5-Methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects.Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation.Melatonin enhances mitochondrial ATP synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2-related factor 2 resulting in activation of phase-2 antioxidant enzymes (γ-GCS, HO-1, NQO1) in ultraviolMelatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions.Melatonin, mitochondria, and the skin.Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.
P2860

Melatonin prevents ultraviolet radiation-induced alterations in plasma membrane potential and intracellular pH in human keratinocytes.

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http://www.wikidata.org/entity/Q47310855
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
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2012年學術文章
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2012年學術文章
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name
Melatonin prevents ultraviolet ...... lar pH in human keratinocytes.
@en
Melatonin prevents ultraviolet ...... lar pH in human keratinocytes.
@nl
type
label
Melatonin prevents ultraviolet ...... lar pH in human keratinocytes.
@en
Melatonin prevents ultraviolet ...... lar pH in human keratinocytes.
@nl
prefLabel
Melatonin prevents ultraviolet ...... lar pH in human keratinocytes.
@en
Melatonin prevents ultraviolet ...... lar pH in human keratinocytes.
@nl
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Melatonin prevents ultraviolet ...... ular pH in human keratinocytes
@en
P2093
P2860
P304
P31
P356
10.1111/J.1600-079X.2012.01028.X
P433
P478
P50
P577
P5875
P698
P921