Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

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http://www.wikidata.org/entity/Q47627028
CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance.High-Throughput Approaches to Pinpoint Function within the Noncoding Genome.Application of CRISPR-Cas9 Based Genome-Wide Screening Approaches to Study Cellular Signalling Mechanisms.Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models.RIOK1 kinase activity is required for cell survival irrespective of MTAP status.Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in cellsUnsupervised correction of gene-independent cell responses to CRISPR-Cas9 targetingProtein interaction and functional data indicate MTHFD2 involvement in RNA processing and translationESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based ModelingImproved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integrationContribution of allelic imbalance to colorectal cancerp53 activation: a checkpoint for precision genome editing?Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasisRecent advances in combinatorial drug screening and synergy scoring
P2860

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

Item
http://www.wikidata.org/entity/Q47627028
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2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
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2017年學術文章
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name
Computational correction of co ...... ality screens in cancer cells.
@en
Computational correction of co ...... ality screens in cancer cells.
@nl
type
label
Computational correction of co ...... ality screens in cancer cells.
@en
Computational correction of co ...... ality screens in cancer cells.
@nl
prefLabel
Computational correction of co ...... ality screens in cancer cells.
@en
Computational correction of co ...... ality screens in cancer cells.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
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P1476
Computational correction of co ...... iality screens in cancer cells
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932