Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update.
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A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malariaPhysiological parameters for oral delivery and in vitro testingRelease of a Poorly Soluble Drug from Hydrophobically Modified Poly (Acrylic Acid) in Simulated Intestinal FluidsColloid formation by drugs in simulated intestinal fluid.A novel beads-based dissolution method for the in vitro evaluation of extended release HPMC matrix tablets and the correlation with the in vivo dataPerturbation of the small intestine microbial ecology by streptomycin alters pathology in a Salmonella enterica serovar typhimurium murine model of infectionStatistical comparison of dissolution profiles to predict the bioequivalence of extended release formulations.Achieving antral grinding forces in biorelevant in vitro models: comparing the USP dissolution apparatus II and the dynamic gastric model with human in vivo data.Epithelial microvilli establish an electrostatic barrier to microbial adhesionThe use of biorelevant dissolution media to forecast the in vivo performance of a drug.Lipid-polymer composite microspheres for colon-specific drug delivery prepared using an ultrasonic spray freeze-drying technique.Analytical methods for dissolution testing of nanosized drugs.A physiologically based pharmacokinetic model of the minipig: data compilation and model implementation.Effect of ingested lipids on drug dissolution and release with concurrent digestion: a modeling approach.Mathematical Models to Explore Potential Effects of Supersaturation and Precipitation on Oral Bioavailability of Poorly Soluble Drugs.New Perspectives for Fixed Dose Combinations of Poorly Water-Soluble Compounds: a Case Study with Ezetimibe and Lovastatin.Human Gastrointestinal Juices Intended for Use in In Vitro Digestion Models.Dissolution Profile of Mefenamic Acid Solid Dosage Forms in Two Compendial and Biorelevant (FaSSIF) Media.Characterising lipid lipolysis and its implication in lipid-based formulation development.Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial ActivityPredicting pharmacokinetics of drugs using physiologically based modeling--application to food effectspH-Dependent Solubility and Dissolution Behavior of Carvedilol--Case Example of a Weakly Basic BCS Class II Drug.Population-based mechanistic prediction of oral drug absorptionEffect of Gastric Fluid Volume on the In Vitro Dissolution and In Vivo Absorption of BCS Class II Drugs: a Case Study with NifedipineA biorelevant dissolution stress test device - background and experiences.Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies.Biorelevant in-vitro performance testing of orally administered dosage forms.Dissolution testing of oral modified-release dosage forms.In-vitro dissolution methods for controlled release parenterals and their applicability to drug-eluting stent testing.Coupling biorelevant dissolution methods with physiologically based pharmacokinetic modelling to forecast in-vivo performance of solid oral dosage forms.Pros and cons of methods used for the prediction of oral drug absorption.Drug release from matrix tablets: physiological parameters and the effect of food.Physiologically based pharmacokinetic modeling in drug discovery and development: a pharmaceutical industry perspective.In vitro-in vivo correlations: general concepts, methodologies and regulatory applications.Intestinal solubility and absorption of poorly water soluble compounds: predictions, challenges and solutions.Mesoporous silica-based dosage forms improve bioavailability of poorly soluble drugs in pigs: case example fenofibrate.Exploring and validating physicochemical properties of mangiferin through GastroPlus® software.Oral uptake of nanoparticles: human relevance and the role of in vitro systems.Dissolution test for risk assessment of nanoparticles: a pilot study.Computational prediction of drug solubility in fasted simulated and aspirated human intestinal fluid.
P2860
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P2860
Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Dissolution media simulating c ...... rointestinal tract: an update.
@en
Dissolution media simulating c ...... rointestinal tract: an update.
@nl
type
label
Dissolution media simulating c ...... rointestinal tract: an update.
@en
Dissolution media simulating c ...... rointestinal tract: an update.
@nl
prefLabel
Dissolution media simulating c ...... rointestinal tract: an update.
@en
Dissolution media simulating c ...... rointestinal tract: an update.
@nl
P2093
P1476
Dissolution media simulating c ...... rointestinal tract: an update.
@en
P2093
Christos Reppas
Ekarat Jantratid
Jennifer B Dressman
Niels Janssen
P304
P356
10.1007/S11095-008-9569-4
P577
2008-04-11T00:00:00Z