SREBPs suppress IRS-2-mediated insulin signalling in the liver. - Wikidata - awgldk - TriplyDB

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

http://www.wikidata.org/entity/Q47868873

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The blind men 'see' the elephant-the many faces of fatty liver disease Involvement of the PA28 -Dependent Pathway in Insulin Resistance Induced by Hepatitis C Virus Core Protein Molecular mechanisms of insulin resistance in chronic hepatitis C Chromatin remodeling complex interacts with ADD1/SREBP1c to mediate insulin-dependent regulation of gene expression PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes Molecular mechanisms involved in hepatic steatosis and insulin resistance.Effect of Lactic Acid Bacteria on Lipid Metabolism and Fat Synthesis in Mice Fed a High-fat Diet.Insulin sensitization of human preadipocytes through glucocorticoid hormone induction of forkhead transcription factors Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism Insulin signaling, resistance, and the metabolic syndrome: insights from mouse models into disease mechanisms.FOXO3a mediates signaling crosstalk that coordinates ubiquitin and atrogin-1/MAFbx expression during glucocorticoid-induced skeletal muscle atrophy Transcriptional feedback control of insulin receptor by dFOXO/FOXO1.The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth Insulin concentration modulates hepatic lipid accumulation in mice in part via transcriptional regulation of fatty acid transport proteins.SREBF1 gene variations modulate insulin sensitivity in response to a fish oil supplementation The A2b adenosine receptor modulates glucose homeostasis and obesity Acetylcholinesterase (AChE) inhibition aggravates fasting-induced triglyceride accumulation in the mouse liver Identifying gene-gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts.Transcriptome analysis of genes regulated by cholesterol loading in two strains of mouse macrophages associates lysosome pathway and ER stress response with atherosclerosis susceptibility Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism.Frontier of epilepsy research - mTOR signaling pathway.Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.FoxO feedback control of basal IRS-2 expression in pancreatic β-cells is distinct from that in hepatocytes Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance.FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis.Rice Bran Protein Hydrolysates Improve Insulin Resistance and Decrease Pro-inflammatory Cytokine Gene Expression in Rats Fed a High Carbohydrate-High Fat Diet A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells Expanding roles for SREBP in metabolism Inflammatory mechanisms in the regulation of insulin resistance.Transcriptional regulation by insulin: from the receptor to the gene.Restoration of euglycemia after duodenal bypass surgery is reliant on central and peripheral inputs in Zucker fa/fa rats.Nutrigenomics, beta-cell function and type 2 diabetes A novel JNK2/SREBP-1c pathway involved in insulin-induced fatty acid synthesis in human adipocytes.The FoxO transcription factors and metabolic regulation.

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SREBPs suppress IRS-2-mediated insulin signalling in the liver.

http://www.wikidata.org/entity/Q47868873

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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name

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

@en

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

@nl

type

label

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

@en

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

@nl

prefLabel

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

@en

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

@nl

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Nature Cell Biology

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SREBPs suppress IRS-2-mediated insulin signalling in the liver.

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P2093

Akimitsu Takahashi

http://www.w3.org/2001/XMLSchema#string

Akiyoshi Fukamizu

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Hideo Toyoshima

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Hiroaki Suzuki

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Hitoshi Shimano

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Masanori Nakakuki

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Nobuhiro Yamada

http://www.w3.org/2001/XMLSchema#string

Takashi Matsuzaka

http://www.w3.org/2001/XMLSchema#string

Takashi Yamamoto

http://www.w3.org/2001/XMLSchema#string

Tomohiro Ide

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351-357

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scholarly article

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10.1038/NCB1111

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4

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6

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2004-03-14T00:00:00Z

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8652955

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15048126

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