Simultaneous and comprehensive in vivo analysis of cytochrome P450 activity by using a cocktail approach in rats.
about
Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA.Evaluation of the impact of Flos Daturae on rat hepatic cytochrome P450 enzymes by cocktail probe drugs.Quantitative prediction of the extent of drug-drug interaction using a physiologically based pharmacokinetic model that includes inhibition of drug metabolism determined in cryopreserved hepatocytes.Unbound liver concentration is the true inhibitor concentration that determines cytochrome P450-mediated drug-drug interactions in rat liver.
P2860
Simultaneous and comprehensive in vivo analysis of cytochrome P450 activity by using a cocktail approach in rats.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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name
Simultaneous and comprehensive ...... g a cocktail approach in rats.
@en
Simultaneous and comprehensive ...... g a cocktail approach in rats.
@nl
type
label
Simultaneous and comprehensive ...... g a cocktail approach in rats.
@en
Simultaneous and comprehensive ...... g a cocktail approach in rats.
@nl
prefLabel
Simultaneous and comprehensive ...... g a cocktail approach in rats.
@en
Simultaneous and comprehensive ...... g a cocktail approach in rats.
@nl
P2093
P2860
P356
P1476
Simultaneous and comprehensive ...... g a cocktail approach in rats.
@en
P2093
Noriyuki Namiki
Shimako Tanaka
Shinya Uchida
P2860
P304
P356
10.1002/BDD.1888
P577
2014-02-04T00:00:00Z