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The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal regionUbiquitination regulates PTEN nuclear import and tumor suppressionThe PEA-15 protein regulates autophagy via activation of JNKSCCRO promotes glioma formation and malignant progression in miceMolecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomasMAPK pathway activation in pilocytic astrocytomaWill kinase inhibitors make it as glioblastoma drugs?Loss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era.Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant gliomaNovel germline mutations in the PTEN tumour suppressor gene found in women with multiple cancersNuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifsStructural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancerPTEN gene and integrin signaling in cancer.Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity.Electrochemical coupling in the voltage-dependent phosphatase Ci-VSP.Phenotype vs genotype in the evolution of astrocytic brain tumors.miR-34a functions as a tumor suppressor modulating EGFR in glioblastoma multiformeRare mutations of the DMBT1 gene in human astrocytic gliomas.Connective tissue growth factor associated with oncogenic activities and drug resistance in glioblastoma multiformePten signaling in gliomas.Gangliogliomas: an intriguing tumor entity associated with focal epilepsies.Genetic alterations associated with adult diffuse astrocytic tumors.Negative Regulation of Receptor Tyrosine Kinase (RTK) Signaling: A Developing FieldOligodendroglioma: toward molecular definitions in diagnostic neuro-oncology.Genetic alterations of human brain tumors as molecular prognostic factors.Genetic profile of gliosarcomasEpigenetic PTEN silencing in malignant melanomas without PTEN mutation.Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cellsPTEN is a target of chromosome 10q loss in anaplastic oligodendrogliomas and PTEN alterations are associated with poor prognosismiR-93 promotes cell proliferation in gliomas through activation of PI3K/Akt signaling pathway.Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization.Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qter.Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast.Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas.Clinicopathological significance of PTEN and bcl2 expressions in oral squamous cell carcinoma'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis.Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma.Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas.Allelic loss of 10q23, the PTEN tumour suppressor gene locus, in Barrett's oesophagus-associated adenocarcinoma.Genetic abnormalities detected in ependymomas by comparative genomic hybridisation.
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
PTEN mutations in gliomas and glioneuronal tumors.
@en
PTEN mutations in gliomas and glioneuronal tumors.
@nl
type
label
PTEN mutations in gliomas and glioneuronal tumors.
@en
PTEN mutations in gliomas and glioneuronal tumors.
@nl
prefLabel
PTEN mutations in gliomas and glioneuronal tumors.
@en
PTEN mutations in gliomas and glioneuronal tumors.
@nl
P2093
P356
P1433
P1476
PTEN mutations in gliomas and glioneuronal tumors
@en
P2093
B Meyer-Puttlitz
B Rollbrocker
O D Wiestler
P2888
P304
P356
10.1038/SJ.ONC.1201756
P407
P577
1998-04-01T00:00:00Z