Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
about
The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNAConstruction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell lineNovel insights into mitotic chromosome condensationDual role of topoisomerase II in centromere resolution and aurora B activityTopoisomerase II-mediated DNA damage is differently repaired during the cell cycle by non-homologous end joining and homologous recombinationCoordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance.Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells.Quantitative analysis of chromosome condensation in fission yeast.A novel chromatin tether domain controls topoisomerase IIα dynamics and mitotic chromosome formation.Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogueTOP2β is essential for ovarian follicles that are hypersensitive to chemotherapeutic drugsMitotic chromosomes are constrained by topoisomerase II-sensitive DNA entanglements.A novel role for ATM in regulating proteasome-mediated protein degradation through suppression of the ISG15 conjugation pathway.The use of divalent metal ions by type II topoisomerases.Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants.The analysis of mutant alleles of different strength reveals multiple functions of topoisomerase 2 in regulation of Drosophila chromosome structure.Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.The NuRD nucleosome remodelling complex and NHK-1 kinase are required for chromosome condensation in oocytes.Decondensing the protamine domain for transcriptionAberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogaster.BAF complexes facilitate decatenation of DNA by topoisomerase IIαPackaging the genome: the structure of mitotic chromosomesThe DNA cleavage reaction of topoisomerase II: wolf in sheep's clothingSUMO modification of DNA topoisomerase II: trying to get a CENse of it allSubstituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity.Topoisomerase II: a fitted mechanism for the chromatin landscape.Bloom helicase and DNA topoisomerase IIIalpha are involved in the dissolution of sister chromatids.The α isoform of topoisomerase II is required for hypercompaction of mitotic chromosomes in human cells.Genome organization during the cell cycle: unity in division.Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells.NK314, a topoisomerase II inhibitor that specifically targets the alpha isoform.C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.Mitosis-specific MPM-2 phosphorylation of DNA topoisomerase IIalpha is regulated directly by protein phosphatase 2A.cin-4, a gene with homology to topoisomerase II, is required for centromere resolution by cohesin removal from sister kinetochores during mitosis.pRb and condensin--local control of global chromosome structureMitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIαRoles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.Selective silencing of DNA topoisomerase IIβ in human mesenchymal stem cells by siRNAs (small interfering RNAs).A Topology-Centric View on Mitotic Chromosome Architecture.DNA damage response during chromatin remodeling in elongating spermatids of mice.
P2860
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P2860
Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
@en
Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
@nl
type
label
Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
@en
Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
@nl
prefLabel
Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
@en
Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
@nl
P356
P1476
Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
@en
P2093
Akihiko Kikuchi
Ayako Sakaguchi
P304
P356
10.1242/JCS.00977
P407
P577
2004-03-01T00:00:00Z