A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions.

A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions.

Item
http://www.wikidata.org/entity/Q48160955
Inhibition of GLI1 gene activation by Patched1Novel mechanism of action on Hedgehog signaling by a suppressor of fused carboxy terminal variantMice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasiaGenetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1.DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differencesBortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma.Regulation of human PTCH1b expression by different 5' untranslated region cis-regulatory elements.Patched knockout mouse models of Basal cell carcinoma.RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signalingNovel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signalMethylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.Selective haploinsufficiency of longer isoforms of PTCH1 protein can cause nevoid basal cell carcinoma syndrome.
P2860

A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions.

Item
http://www.wikidata.org/entity/Q48160955
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
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2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
A novel first exon of the Patc ...... pathway inhibitory functions.
@en
A novel first exon of the Patc ...... pathway inhibitory functions.
@nl
type
label
A novel first exon of the Patc ...... pathway inhibitory functions.
@en
A novel first exon of the Patc ...... pathway inhibitory functions.
@nl
prefLabel
A novel first exon of the Patc ...... pathway inhibitory functions.
@en
A novel first exon of the Patc ...... pathway inhibitory functions.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
A novel first exon of the Patc ...... pathway inhibitory functions.
@en
P2093
P2860
P304
P31
P356
10.1016/J.FEBSLET.2004.11.006
P407
P433
P478
P50
P577
P5875
P698