A synthetic combinatorial approach to disabling deviant Hedgehog signaling.

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A synthetic combinatorial approach to disabling deviant Hedgehog signaling.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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A synthetic combinatorial approach to disabling deviant Hedgehog signaling.

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A synthetic combinatorial approach to disabling deviant Hedgehog signaling.

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A synthetic combinatorial approach to disabling deviant Hedgehog signaling.

@en

A synthetic combinatorial approach to disabling deviant Hedgehog signaling.

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A synthetic combinatorial approach to disabling deviant Hedgehog signaling.

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A synthetic combinatorial approach to disabling deviant Hedgehog signaling.

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P1476

A synthetic combinatorial approach to disabling deviant Hedgehog signaling.

@en

P2093

C-W Fan

http://www.w3.org/2001/XMLSchema#string

H Shi

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J Kim

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N Yarravarapu

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O Kulak

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P2860

HDAC6 is a microtubule-associated deacetylase

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

P2888

s41598-018-19408-9

P304

1133

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P31

scholarly article

P356

10.1038/S41598-018-19408-9

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Chuo Chen

Lawrence Lum

P577

2018-01-18T00:00:00Z

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P6179

1100351948

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P698

29348431

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P932

5773580

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