Epigenetic dysregulation in pancreatic islets and pathogenesis of type 2 diabetes.

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Epigenetic dysregulation in pancreatic islets and pathogenesis of type 2 diabetes.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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Epigenetic dysregulation in pancreatic islets and pathogenesis of type 2 diabetes.

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Epigenetic dysregulation in pancreatic islets and pathogenesis of type 2 diabetes.

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Item

label

Epigenetic dysregulation in pancreatic islets and pathogenesis of type 2 diabetes.

@en

Epigenetic dysregulation in pancreatic islets and pathogenesis of type 2 diabetes.

@nl

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Epigenetic dysregulation in pancreatic islets and pathogenesis of type 2 diabetes.

@en

Epigenetic dysregulation in pancreatic islets and pathogenesis of type 2 diabetes.

@nl

P1476

Epigenetic dysregulation in pancreatic islets and pathogenesis of type 2 diabetes.

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P2093

Norihide Yokoi

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P2860

Continuous Aging of the Human DNA Methylome Throughout the Human Lifespan

BSmooth: from whole genome bisulfite sequencing reads to differentially methylated regions

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Integrative analysis of 111 reference human epigenomes

Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes.

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.

Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

P31

scholarly article

P356

10.1111/JDI.12724

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P50

Norihide Yokoi

P577

2017-08-08T00:00:00Z

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P698

28786564

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P921

type-2 diabetes

P932

5934264

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