The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice.
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Low dose pramipexole is neuroprotective in the MPTP mouse model of Parkinson's disease, and downregulates the dopamine transporter via the D3 receptorMitochondrial toxin 3-nitropropionic acid induces cardiac and neurotoxicity differentially in miceMurine motor and behavior functional evaluations for acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxication.The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety.Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease.Importance of monoamine oxidase A in the bioactivation of neurotoxic analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridineTRPC1 inhibits apoptotic cell degeneration induced by dopaminergic neurotoxin MPTP/MPP(+).Gene-environment interaction models to unmask susceptibility mechanisms in Parkinson's disease.Transgenic conversion of omega-6 into omega-3 fatty acids in a mouse model of Parkinson's disease.Olfaction in three genetic and two MPTP-induced Parkinson's disease mouse models.Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson's diseaseLong-lasting transcriptional refractoriness triggered by a single exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine14-3-3 inhibition promotes dopaminergic neuron loss and 14-3-3θ overexpression promotes recovery in the MPTP mouse model of Parkinson's disease.Characteristics of dopaminergic neurotoxicity produced by MPTP and methamphetamine.Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease.Clavulanic acid inhibits MPP⁺-induced ROS generation and subsequent loss of dopaminergic cells.Animal models of Parkinson's disease progressionChronic Exposure to Arsenic in Drinking Water Causes Alterations in Locomotor Activity and Decreases Striatal mRNA for the D2 Dopamine Receptor in CD1 Male Mice.MPTP mouse models of Parkinson's disease: an update.Noradrenergic-Dopaminergic Interactions Due to DSP-4-MPTP Neurotoxin Treatments: Iron Connection.The PPARgamma agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B.Methylenedioxymethamphetamine inhibits mitochondrial complex I activity in mice: a possible mechanism underlying neurotoxicity.Nicotine enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.MK-801 fails to protect against the dopaminergic neuropathology produced by systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice or intranigral 1-methyl-4-phenylpyridinium in rats.Potentiation by the tetraphenylboron anion of the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its pyridinium metabolite.Co-administration of memantine and amantadine with sub/suprathreshold doses of L-Dopa restores motor behaviour of MPTP-treated mice.In vivo complementation of complex I by the yeast Ndi1 enzyme. Possible application for treatment of Parkinson disease.Quantitative gene expression profiling of mouse brain regions reveals differential transcripts conserved in human and affected in disease models.Pre-clinical therapeutic development of a series of metalloporphyrins for Parkinson's disease.MPTP animal model of Parkinsonism: dopamine cell death or only tyrosine hydroxylase impairment? A study using PET imaging, autoradiography, and immunohistochemistry in the cat.Acute and chronic administration of ibogaine to the rat results in astrogliosis that is not confined to the cerebellar vermis.[3H]1-methyl-4-phenyl-2,3-dihydropyridinium ion binding sites in mouse brain: pharmacological and biological characterization.Reduced calcium/calmodulin-dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice.An Enriched Environment Ameliorates Oxidative Stress and Olfactory Dysfunction in Parkinson's Disease with α-Synucleinopathy.Relative resistance of rabbits to MPTP neurotoxicity.Connexin 30 deficiency attenuates A2 astrocyte responses and induces severe neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Parkinson's disease animal model
P2860
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P2860
The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
The influence of dose and dosi ...... inergic neurotoxicity in mice.
@en
The influence of dose and dosi ...... inergic neurotoxicity in mice.
@nl
type
label
The influence of dose and dosi ...... inergic neurotoxicity in mice.
@en
The influence of dose and dosi ...... inergic neurotoxicity in mice.
@nl
prefLabel
The influence of dose and dosi ...... inergic neurotoxicity in mice.
@en
The influence of dose and dosi ...... inergic neurotoxicity in mice.
@nl
P1476
The influence of dose and dosi ...... inergic neurotoxicity in mice.
@en
P2093
Heikkila RE
Sonsalla PK
P304
P356
10.1016/0014-2999(86)90444-9
P407
P577
1986-10-01T00:00:00Z