Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease. - Wikidata - awgldk - TriplyDB

Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease.

Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease.

http://www.wikidata.org/entity/Q48302165

about

The role of oxidative stress in Parkinson's disease Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity Central nervous system toxicity of metallic nanoparticles Application of dental nanomaterials: potential toxicity to the central nervous system Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease.Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants.Nitrated alpha-synuclein and microglial neuroregulatory activities.Microglia acquire distinct activation profiles depending on the degree of alpha-synuclein neuropathology in a rAAV based model of Parkinson's disease.Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies.Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia Voltage-gated proton channels find their dream job managing the respiratory burst in phagocytes.Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target.Dual destructive and protective roles of adaptive immunity in neurodegenerative disorders.Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease.Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy.Mechanisms Underlying Interferon-γ-Induced Priming of Microglial Reactive Oxygen Species Production.Elevated expression of chloride intracellular channel 1 is correlated with poor prognosis in human gliomas.Redox imbalance in Parkinson's disease.Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration.Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets A macrophage-nanozyme delivery system for Parkinson's disease.Immunological features of alpha-synuclein in Parkinson's disease.Neuroinflammation and oxidation/nitration of alpha-synuclein linked to dopaminergic neurodegeneration.Proteomic studies of nitrated alpha-synuclein microglia regulation by CD4+CD25+ T cells.Innate and adaptive immunity for the pathobiology of Parkinson's disease Oxidative stress induces gastric submucosal arteriolar dysfunction in the elderly.Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes.Chloride intracellular channel 1 (CLIC1): Sensor and effector during oxidative stress.Immunotherapy for neurodegenerative diseases: focus on α-synucleinopathies.The neuroprotective role of ferrostatin-1 under rotenone-induced oxidative stress in dopaminergic neuroblastoma cells.Endocannabinoid system in neurodegenerative disorders.Amyloid-β-induced reactive oxygen species production and priming are differentially regulated by ion channels in microglia.Mutant alpha-synuclein overexpression mediates early proinflammatory activity.Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease.α-Synuclein Alters Toll-Like Receptor Expression Charge compensation for NADPH oxidase activity in microglia in rat brain slices does not involve a proton current.

P2860

Q24307946-289EE4C4-CF2A-4238-BE70-BCE633F66EF4 Q26830542-00A8F492-78CE-4FC3-9C0F-F28D7694CCB6 Q26853537-5C779044-D281-4039-B7C1-AC533038F5BD Q27027973-3D240143-5487-4AD9-A94F-34A11DEE6F72 Q28084729-AEFA9E10-647A-47FF-8A90-B8D5E1AC17C6 Q28394487-D24F7382-47F6-49FC-805A-DAA8D979F7AC Q28681630-21EB2F9B-0E2F-4EF2-AF1B-EEE90DED7480 Q30000089-6F828BC4-849A-4FF4-9B6B-8F47C90D59C0 Q30493249-E6FA53C0-C1AD-4F79-AE9D-558D2C5BD350 Q30991616-0BD09D09-C3D1-474D-9515-98C7BE855C42 Q33315262-4F68344F-E84F-4426-AA07-4F872A375061 Q33526342-9D8DD761-79B4-4D78-BE35-A788696831BB Q33726660-8417A2D2-41FB-4302-845F-E52446EFE56F Q33874305-A8618FEF-7AC2-4299-86BC-A57BE71F333D Q34505320-E22B838F-57D9-4BFB-92E4-19CF02653892 Q34680801-DC30B252-B104-4D28-AB26-3DFD2EEDC09A Q35068792-9C8DE217-04A0-4955-8722-D25D20AA1A3C Q35942562-1D0D3E6A-4FCB-43EB-B2E5-7A1F9F53BCE6 Q36085162-3A8ED64D-E173-42FC-B12C-5A3DA4A17ACB Q36123919-8D72DAC1-05E9-4F86-B41B-17BF5452950E Q36232115-5D37848C-2EB4-4AB5-B76C-774ADAC7793C Q36899782-EFC17237-4D36-4CEF-81FB-CDE6AA215496 Q37132290-E8A998FB-8E46-45BF-A988-61B2C3321949 Q37137351-1BE1E703-E827-42C3-ABF1-3EAABEB7AEC0 Q37179637-9DC12AC6-1181-484D-B0CF-6232FF83FF02 Q37232067-D05C74C0-E44E-42A8-A515-0AA0128456B6 Q37241917-B8BB93CC-9DBB-436F-A36B-E18A02E97CB9 Q37355257-1400B072-CFF6-44B9-9334-BA8B314A3FCD Q37401280-AF8226B0-1680-4155-B571-3941818A567E Q37440025-607F2E28-F896-4123-99BA-CB65C594BF91 Q37653023-9D3F3727-2D20-4840-989D-330F18A9C4F5 Q37729392-3002B899-C15E-4729-B190-7378930C5453 Q38079317-7E7623F3-EF1D-4A81-92E6-1B0CB5D4AFCE Q38834181-EFF2FBF2-3D64-4353-B62D-CE4510146DD6 Q39368845-6DBCD6E4-70A9-4813-8C92-4375704A87C5 Q39592033-4F335026-733E-40C7-AB29-994CAC9DB24F Q40778644-A3A294C7-79FD-40E8-9A54-8A0BC0A4CB02 Q42521775-EA1A3ABE-3B8A-44CC-90CB-E0C0BF532A3E Q42783371-1AFDF243-34C9-4EEC-813C-14DEFBA9AB96 Q43164978-73E0AE13-3664-4606-841E-9302D855F6B2

P2860

Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease.

http://www.wikidata.org/entity/Q48302165

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh

2007年學術文章

@zh-hant

name

Ion channel blockade attenuate ...... enesis of Parkinson's disease.

@en

Ion channel blockade attenuate ...... enesis of Parkinson's disease.

@nl

type

label

Ion channel blockade attenuate ...... enesis of Parkinson's disease.

@en

Ion channel blockade attenuate ...... enesis of Parkinson's disease.

@nl

prefLabel

Ion channel blockade attenuate ...... enesis of Parkinson's disease.

@en

Ion channel blockade attenuate ...... enesis of Parkinson's disease.

@nl

P1433

Q48302165-25871D9D-9ECC-4348-9DA1-336DC8C0CA8F

P1476

Q48302165-282C4DA4-AA41-430D-B53F-CF94C5A38498

P2093

Q48302165-1CFD285E-09D5-48E1-BE8D-1E1F7F8308FC

Q48302165-28165BA3-A695-4339-BF8D-C0915557C09B

Q48302165-33061B00-F1C4-475F-BCD2-F4A4A446BC95

Q48302165-68D3F2EE-D88B-48AC-A74D-2FFDC4852229

Q48302165-EE074B8F-AF75-49C1-B91B-1AE8EC8DE43D

P2860

Q48302165-000FFE4E-D6F9-4151-8B0F-FD9498B50D56

Q48302165-0212C8E8-B336-479F-9028-E096BB7C8D7C

Q48302165-1592E872-53C9-497F-B9A4-8600259C75AC

Q48302165-17E4E028-F5C7-4B06-B3AD-11B513465D1B

Q48302165-2008E398-3420-45DA-A9CB-61543E537141

Q48302165-2CB17A8D-EB7C-4623-B643-A4942BEF2A93

Q48302165-34BF718A-6476-4B65-9A25-85B6CB23A5BE

Q48302165-37CAB22C-6FDA-4EE7-A286-6DD24860F448

Q48302165-3D8BCF0A-3763-42DF-A33A-633FBCA09E7F

Q48302165-411B9C20-D4D3-4EF0-A538-6F9321AFAD70

P304

Q48302165-4FD8C082-39FC-46A6-95C6-452312D7B8C0

P31

Q48302165-25CAE495-4EAB-4D25-BCC8-AB90A51E1EDA

P356

Q48302165-2ED0FFDA-FABA-4BDB-896A-E94D8BFDB5A2

P407

Q48302165-7C55D098-E6CE-4F21-9EC3-07391A3172F1

P433

Q48302165-6DCE5857-5980-4CF9-BA13-AE8B9438391C

P478

Q48302165-03254706-5DEF-488F-B0AC-E7A59A817551

P50

Q48302165-8E8A6317-FD75-472D-9378-E7F518983047

P577

Q48302165-72EF82D7-770D-41CD-87FD-4B0DE46B6BD9

P5875

Q48302165-B40A7A38-5B63-4FF1-89C7-4E8635C4100C

P698

Q48302165-2D36445C-F983-4CD2-9312-3434F5C8C6B6

P921

Q48302165-63E9489B-74E6-40E5-9580-7F1463FAB9A2

Q48302165-C4B674BA-7227-42BB-918E-DEA303DDA27F

Q48302165-EED04F81-27E2-42E1-B71E-FEA206C11A8C

P356

J.1471-4159.2006.04315.X

P1433

Journal of Neurochemistry

P1476

Ion channel blockade attenuate ...... genesis of Parkinson's disease

@en

P2093

Ashley Reynolds

http://www.w3.org/2001/XMLSchema#string

Howard E Gendelman

http://www.w3.org/2001/XMLSchema#string

Mark P Thomas

http://www.w3.org/2001/XMLSchema#string

Ruma Banerjee

http://www.w3.org/2001/XMLSchema#string

Victor Vitvitsky

http://www.w3.org/2001/XMLSchema#string

P2860

Oxidative stress in neurodegeneration: cause or consequence?

Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease

Parkinson's disease: mechanisms and models

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

Oxidative stress in Parkinson's disease

Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease alpha-synuclein fibrillogenesis.

Voltage-gated proton channels in microglia.

Microglia in cell culture and in transplantation therapy for central nervous system disease.

Metabolism and functions of glutathione in brain.

Synucleinopathies: clinical and pathological implications.

P304

503-519

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1111/J.1471-4159.2006.04315.X

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

100

http://www.w3.org/2001/XMLSchema#string

P50

Kathryn M Chartrand

P577

2007-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6562237

http://www.w3.org/2001/XMLSchema#string

P698

17241161

http://www.w3.org/2001/XMLSchema#string

P921

Parkinson's disease