Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys.
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Motor control and aging: links to age-related brain structural, functional, and biochemical effectsParkinson's disease as a result of agingNeuron-specific age-related decreases in dopamine receptor subtype mRNAsA monoclonal antibody-GDNF fusion protein is not neuroprotective and is associated with proliferative pancreatic lesions in parkinsonian monkeysThe effect of acute exercise and psychosocial stress on fine motor skills and testosterone concentration in the saliva of high school students.Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice.Autologous mesenchymal stem cell-derived dopaminergic neurons function in parkinsonian macaques.Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease.Nonuniform cardiac denervation observed by 11C-meta-hydroxyephedrine PET in 6-OHDA-treated monkeysAging reveals a role for nigral tyrosine hydroxylase ser31 phosphorylation in locomotor activity generation.Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primatesGlial cell line-derived neurotrophic factor gene therapy ameliorates chronic hyperprolactinemia in senile rats.Nontropic actions of neurotrophins: subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation.Evaluation of hydrodynamic limb vein injections in nonhuman primates.Systemic administration of 6-OHDA to rhesus monkeys upregulates HLA-DR expression in brain microvasculatureResponse of aged parkinsonian monkeys to in vivo gene transfer of GDNFOncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's diseaseAged monkeys as a partial model for Parkinson's disease.The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys.Age- and duration-dependent effects of MPTP on cortical serotonin systemsAge-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapyRelationships among cognitive function, fine motor speed and age in the rhesus monkey.Lost in transition: aging-related changes in executive control by the medial prefrontal cortex.Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates.Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys.α-Synuclein and nonhuman primate models of Parkinson's diseaseAging and physical mobility in group-housed Old World monkeysInitiation of calorie restriction in middle-aged male rats attenuates aging-related motoric decline and bradykinesia without increased striatal dopamine.Levodopa increases memory encoding and dopamine release in the striatum in the elderly.Pharmacologic MRI (phMRI) as a tool to differentiate Parkinson's disease-related from age-related changes in basal ganglia function.Effects of aging and levodopa on the laryngeal adductor reflex in ratsBehavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice.Effect of age and caloric restriction on circadian adrenal steroid rhythms in rhesus macaques.Exercise-Mediated Increase in Nigral Tyrosine Hydroxylase Is Accompanied by Increased Nigral GFR-α1 and EAAC1 Expression in Aging RatsIntracerebral transplantation of differentiated human embryonic stem cells to hemiparkinsonian monkeys.Neuroprotective Properties of a Novel Non-Thiazoledinedione Partial PPAR- γ Agonist against MPTP.Large animal models of neurological disorders for gene therapy.Decreased expression of ErbB4 and tyrosine hydroxylase mRNA and protein in the ventral midbrain of aged rats.Clinically relevant effects of convection-enhanced delivery of AAV2-GDNF on the dopaminergic nigrostriatal pathway in aged rhesus monkeys.Future of cell and gene therapies for Parkinson's disease.
P2860
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P2860
Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Age-related declines in nigral ...... impairments in rhesus monkeys.
@en
Age-related declines in nigral ...... impairments in rhesus monkeys.
@nl
type
label
Age-related declines in nigral ...... impairments in rhesus monkeys.
@en
Age-related declines in nigral ...... impairments in rhesus monkeys.
@nl
prefLabel
Age-related declines in nigral ...... impairments in rhesus monkeys.
@en
Age-related declines in nigral ...... impairments in rhesus monkeys.
@nl
P2093
P1476
Age-related declines in nigral ...... impairments in rhesus monkeys.
@en
P2093
Kordower JH
P304
P356
10.1002/(SICI)1096-9861(19981116)401:2<253::AID-CNE7>3.3.CO;2-O
P407
P577
1998-11-01T00:00:00Z