Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas.
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Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion.A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children.Integrated analysis of miRNA and mRNA expression in childhood medulloblastoma compared with neural stem cellsElevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells.Identification of suitable endogenous control genes for microRNA expression profiling of childhood medulloblastoma and human neural stem cellsThe SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cellsMedullospheres from DAOY, UW228 and ONS-76 cells: increased stem cell population and proteomic modificationsIsolation of distinct cell populations from the developing cerebellum by microdissection.Gene expression analyses of the spatio-temporal relationships of human medulloblastoma subgroups during early human neurogenesisAn animal model of MYC-driven medulloblastomaConverging miRNA functions in diverse brain disorders: a case for miR-124 and miR-126.Adenomatous polyposis coli is essential for both neuronal differentiation and maintenance of adult neural stem cells in subventricular zone and hippocampus.Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.Adult medulloblastoma: A rare case report and literature review.The retinoblastoma tumor suppressor and stem cell biology.Consensus Paper: Cerebellar Development.A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity.Expression of BARHL1 in medulloblastoma is associated with prolonged survival in mice and humans.Brain tumor stem cells: the cancer stem cell hypothesis writ large.Review: personalized mice: modelling the molecular heterogeneity of medulloblastoma.Oncogenic challenges in stem cells and the link to cancer initiation.Medulloblastoma stem cells: where development and cancer cross pathways.The SOX family of genes in cancer development: biological relevance and opportunities for therapy.What underlies the diversity of brain tumors?Sox2: regulation of expression and contribution to brain tumors.SOX9 Overexpression Promotes Glioma Metastasis via Wnt/β-Catenin Signaling.FoxG1 interacts with Bmi1 to regulate self-renewal and tumorigenicity of medulloblastoma stem cells.WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma.Oncogenic role of SOX9 expression in human malignant glioma.Medulloblastoma: experimental models and reality.Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells.Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma.Celecoxib enhances radiosensitivity in medulloblastoma-derived CD133-positive cells.Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor cellsNanog, Gli, and p53: a new network of stemness in development and cancer.The histone deacetylase inhibitor sodium butyrate promotes cell death and differentiation and reduces neurosphere formation in human medulloblastoma cells.Novel gene expression model for outcome prediction in paediatric medulloblastoma.Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation.Nuclear Localization Signal-Enhanced Polyurethane-Short Branch Polyethylenimine-Mediated Delivery of Let-7a Inhibited Cancer Stem-Like Properties by Targeting the 3'-UTR of HMGA2 in Anaplastic Astrocytoma.MicroRNA142-3p promotes tumor-initiating and radioresistant properties in malignant pediatric brain tumors.
P2860
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P2860
Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Cerebellar stem cells act as m ...... set of human medulloblastomas.
@en
Cerebellar stem cells act as m ...... set of human medulloblastomas.
@nl
type
label
Cerebellar stem cells act as m ...... set of human medulloblastomas.
@en
Cerebellar stem cells act as m ...... set of human medulloblastomas.
@nl
prefLabel
Cerebellar stem cells act as m ...... set of human medulloblastomas.
@en
Cerebellar stem cells act as m ...... set of human medulloblastomas.
@nl
P2093
P2860
P50
P356
P1433
P1476
Cerebellar stem cells act as m ...... set of human medulloblastomas.
@en
P2093
A Santuccione
F L Heppner
O Shakhova
P2860
P2888
P304
P356
10.1038/ONC.2009.472
P407
P577
2010-01-11T00:00:00Z