Rheostatic Control of Cas9-Mediated DNA Double Strand Break (DSB) Generation and Genome Editing.

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Rheostatic Control of Cas9-Mediated DNA Double Strand Break (DSB) Generation and Genome Editing.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

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2017年學術文章

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name

Rheostatic Control of Cas9-Med ...... Generation and Genome Editing.

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Rheostatic Control of Cas9-Mediated DNA Double Strand Break

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type

Item

label

Rheostatic Control of Cas9-Med ...... Generation and Genome Editing.

@en

Rheostatic Control of Cas9-Mediated DNA Double Strand Break

@nl

prefLabel

Rheostatic Control of Cas9-Med ...... Generation and Genome Editing.

@en

Rheostatic Control of Cas9-Mediated DNA Double Strand Break

@nl

P1476

Rheostatic Control of Cas9-Med ...... Generation and Genome Editing.

@en

P2093

Cindy T Wei

http://www.w3.org/2001/XMLSchema#string

Douglas M Fowler

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Jason J Stephany

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P2860

Structure-guided design of a selective BCL-X(L) inhibitor

A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity.

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.

Rationally engineered Cas9 nucleases with improved specificity.

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding.

Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition.

P304

438-442

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P31

scholarly article

P356

10.1021/ACSCHEMBIO.7B00652

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

John C Rose

Dustin J Maly

P577

2017-09-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28895730

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P932

5821106

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