Targeted disruption of the PEPT2 gene markedly reduces dipeptide uptake in choroid plexus.
about
Mouse endogenous retroviruses can trigger premature transcriptional termination at a distanceTargeted disruption of the peptide transporter Pept2 gene in mice defines its physiological role in the kidney.Molecular mechanisms of pulmonary peptidomimetic drug and peptide transport.High-affinity peptide transporter PEPT2 (SLC15A2) of the zebrafish Danio rerio: functional properties, genomic organization, and expression analysis.From bacteria to man: archaic proton-dependent peptide transporters at work.Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of Pept2-/- mice.Enhanced antinociceptive response to intracerebroventricular kyotorphin in Pept2 null miceSignificance and regional dependency of peptide transporter (PEPT) 1 in the intestinal permeability of glycylsarcosine: in situ single-pass perfusion studies in wild-type and Pept1 knockout miceDistribution of glycylsarcosine and cefadroxil among cerebrospinal fluid, choroid plexus, and brain parenchyma after intracerebroventricular injection is markedly different between wild-type and Pept2 null miceDivergent developmental expression and function of the proton-coupled oligopeptide transporters PepT2 and PhT1 in regional brain slices of mouse and ratDrug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models.Choroid plexus transport: gene deletion studies.PEPT2-mediated transport of 5-aminolevulinic acid and carnosine in astrocytes.Protective effects of isothiocyanates on blood-CSF barrier disruption induced by oxidative stress.Chemical modification and formulation approaches to elevated drug transport across cell membranes.Impaired monoamine and organic cation uptake in choroid plexus in mice with targeted disruption of the plasma membrane monoamine transporter (Slc29a4) gene.Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications.Xenobiotic transporters: ascribing function from gene knockout and mutation studies.Population pharmacokinetic modeling of cefadroxil renal transport in wild-type and Pept2 knockout micePharmaceutical and pharmacological importance of peptide transporters.Influence of genetic knockout of Pept2 on the in vivo disposition of endogenous and exogenous carnosine in wild-type and Pept2 null mice.Role and relevance of PEPT2 in drug disposition, dynamics, and toxicityImportance of Peptide transporter 2 on the cerebrospinal fluid efflux kinetics of glycylsarcosine characterized by nonlinear mixed effects modeling.Polymorphisms of delta-aminolevulinic acid dehydratase (ALAD) and peptide transporter 2 (PEPT2) genes in children with low-level lead exposure.Transport of drugs by proton-coupled peptide transporters: pearls and pitfalls.Advances in the use of prodrugs for drug delivery to the eye.Expression of proton-coupled oligopeptide transporter (POTs) in prostate of mice and patients with benign prostatic hyperplasia (BPH) and prostate cancer (PCa).Genetic Method for Labeling Electrically Coupled Cells: Application to Retina.Kyotorphin transport and metabolism in rat and mouse neonatal astrocytes.Carnosine uptake in rat choroid plexus primary cell cultures and choroid plexus whole tissue from PEPT2 null mice.Influence of peptide transporter 2 (PEPT2) on the distribution of cefadroxil in mouse brain: A microdialysis study.Carnosine and cancer: a perspective.
P2860
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P2860
Targeted disruption of the PEPT2 gene markedly reduces dipeptide uptake in choroid plexus.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Targeted disruption of the PEP ...... tide uptake in choroid plexus.
@en
Targeted disruption of the PEP ...... tide uptake in choroid plexus.
@nl
type
label
Targeted disruption of the PEP ...... tide uptake in choroid plexus.
@en
Targeted disruption of the PEP ...... tide uptake in choroid plexus.
@nl
prefLabel
Targeted disruption of the PEP ...... tide uptake in choroid plexus.
@en
Targeted disruption of the PEP ...... tide uptake in choroid plexus.
@nl
P2093
P2860
P356
P1476
Targeted disruption of the PEP ...... tide uptake in choroid plexus.
@en
P2093
David E Smith
Frank C Brosius
Jianming Xiang
P2860
P304
P356
10.1074/JBC.M207397200
P407
P577
2002-12-06T00:00:00Z