Enzymatic activation of voltage-gated potassium channels.
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Interactions between lipids and voltage sensor paddles detected with tarantula toxinsTarantula toxins interact with voltage sensors within lipid membranesSolution Structure and Phospholipid Interactions of the Isolated Voltage-Sensor Domain from KvAPContribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflowBrown spider (Loxosceles genus) venom toxins: tools for biological purposesMembrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.Outer membrane phospholipase A in phospholipid bilayers: a model system for concerted computational and experimental investigations of amino acid side chain partitioning into lipid bilayers.Inhibition of CFTR Cl- channel function caused by enzymatic hydrolysis of sphingomyelin.Molecular dynamics simulation of Kv channel voltage sensor helix in a lipid membrane with applied electric fieldExogenous and endogenous ceramides elicit volume-sensitive chloride current in ventricular myocytes.Functional reconstitution of a voltage-gated potassium channel in giant unilamellar vesicles.Structure and hydration of membranes embedded with voltage-sensing domains.Electrostatic tuning of cellular excitability.Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels.Caveolae, ion channels and cardiac arrhythmias.Reduced voltage sensitivity in a K+-channel voltage sensor by electric field remodeling.Targeting voltage sensors in sodium channels with spider toxins.Bacterial Sphingomyelinase is a State-Dependent Inhibitor of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR)Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domainStructure and orientation of a voltage-sensor toxin in lipid membranes.Sphingomyelinase D activity in model membranes: structural effects of in situ generation of ceramide-1-phosphateCounteracting suppression of CFTR and voltage-gated K+ channels by a bacterial pathogenic factor with the natural product tannic acidStructural interactions between lipids, water and S1-S4 voltage-sensing domainsPosition and motions of the S4 helix during opening of the Shaker potassium channel.Phosphatidic acid modulation of Kv channel voltage sensor function.A shaker K+ channel with a miniature engineered voltage sensor.Elucidating the molecular basis of action of a classic drug: guanidine compounds as inhibitors of voltage-gated potassium channels.Structural interactions of a voltage sensor toxin with lipid membranes.Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations.Structural dynamics of the S4 voltage-sensor helix in lipid bilayers lacking phosphate groups.Two distinct effects of PIP2 underlie auxiliary subunit-dependent modulation of Slo1 BK channels.Functional extension of amino acid triads from the fourth transmembrane segment (S4) into its external linker in Shaker K(+) channels.Palmitoylation influences the function and pharmacology of sodium channels.Sphingomyelinase D inhibits store-operated Ca2+ entry in T lymphocytes by suppressing ORAI current.Molecular dynamics simulations of voltage-gated cation channels: insights on voltage-sensor domain function and modulation.Sphingomyelin, ORAI1 channels, and cellular Ca2+ signaling.Coupling between the voltage-sensing and pore domains in a voltage-gated potassium channel.Osmoregulated Chloride Currents in Hemocytes from Mytilus galloprovincialis.PIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4-S5 linker.bSUM: A bead-supported unilamellar membrane system facilitating unidirectional insertion of membrane proteins into giant vesicles.
P2860
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P2860
Enzymatic activation of voltage-gated potassium channels.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Enzymatic activation of voltage-gated potassium channels.
@en
Enzymatic activation of voltage-gated potassium channels.
@nl
type
label
Enzymatic activation of voltage-gated potassium channels.
@en
Enzymatic activation of voltage-gated potassium channels.
@nl
prefLabel
Enzymatic activation of voltage-gated potassium channels.
@en
Enzymatic activation of voltage-gated potassium channels.
@nl
P2093
P356
P1433
P1476
Enzymatic activation of voltage-gated potassium channels.
@en
P2093
P2888
P304
P356
10.1038/NATURE04880
P407
P577
2006-06-21T00:00:00Z
P5875
P6179
1021268164