Allelic imbalance, including deletion of PTEN/MMACI, at the Cowden disease locus on 10q22-23, in hamartomas from patients with Cowden syndrome and germline PTEN mutation.
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Phosphorylation of the PTEN tail regulates protein stability and functionRegulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathwayMale breast cancer in Cowden syndrome patients with germline PTEN mutationsNew insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathwaySurvey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesionsNeuroendocrine Tumor of the Pancreas as a Manifestation of Cowden Syndrome: A Case ReportMutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity.Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes.Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53.PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome.Contiguous gene deletion within chromosome arm 10q is associated with juvenile polyposis of infancy, reflecting cooperation between the BMPR1A and PTEN tumor-suppressor genes.Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas.Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypesAnalysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma.Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer.Molecular pathology of thyroid cancer: diagnostic and clinical implications.Haplo-insufficiency: a driving force in cancer.PTEN function: the long and the short of it.Enhanced cell growth inhibition following PTEN nonviral gene transfer using polyethylenimine and photochemical internalization in endometrial cancer cells.The expression of tumour suppressors and proto-oncogenes in tissues susceptible to their hereditary cancers.Landscaper seeks remunerative positionWhere Birt-Hogg-Dubé meets Cowden syndrome: mirrored genetic defects in two cases of syndromic oncocytic tumours.Recurrent allelic imbalance at the rat Pten locus in DMBA-induced fibrosarcomas.Germline mutations of the PTEN/MMAC1 gene in Japanese patients with Cowden disease.
P2860
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P2860
Allelic imbalance, including deletion of PTEN/MMACI, at the Cowden disease locus on 10q22-23, in hamartomas from patients with Cowden syndrome and germline PTEN mutation.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Allelic imbalance, including d ...... me and germline PTEN mutation.
@en
Allelic imbalance, including d ...... me and germline PTEN mutation.
@nl
type
label
Allelic imbalance, including d ...... me and germline PTEN mutation.
@en
Allelic imbalance, including d ...... me and germline PTEN mutation.
@nl
altLabel
Allelic imbalance, including d ...... rome and germlinePTEN mutation
@en
prefLabel
Allelic imbalance, including d ...... me and germline PTEN mutation.
@en
Allelic imbalance, including d ...... me and germline PTEN mutation.
@nl
P2093
P2860
P1476
Allelic imbalance, including d ...... me and germline PTEN mutation.
@en
P2093
A L Richardson
A M Goldstein
B G Robinson
F Dorion-Bonnet
P2860
P356
10.1002/(SICI)1098-2264(199801)21:1<61::AID-GCC8>3.0.CO;2-6
P407
P577
1998-01-01T00:00:00Z