Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
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Biological sex and mechanisms of ischemic brain injuryNitric oxide and peroxynitrite in health and diseaseTRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymeraseApoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell deathSrc-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.Beneficial effects of n-acetylcysteine on ischaemic brain injuryRegulated necrotic cell death: the passive aggressive side of Bax and BakNeuronal death induced by misfolded prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment.PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function.Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1Neuroprotective Strategies during Cardiac Surgery with Cardiopulmonary BypassPoly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal deathCellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disordersThe effects of estrogen in ischemic strokeNuclear DNA damage signalling to mitochondria in ageingPARP-1 Inhibition Is Neuroprotective in the R6/2 Mouse Model of Huntington's DiseasePeroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activationInhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the ratPoly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functionsXRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.Estrogen receptor antagonist ICI182,780 exacerbates ischemic injury in female mouse.The effect of PARP inhibitor on ischaemic cell death, its related inflammation and survival signals.NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy.Neuronal death is an active, caspase-dependent process after moderate but not severe DNA damage.Poly(adenosine diphosphate-ribose) synthetase inhibitor 3-aminobenzamide alleviates cochlear dysfunction induced by transient ischemia.Photodynamic therapy combined to cisplatin potentiates cell death responses of cervical cancer cells.Identification and analysis of plasticity-induced late-response genes.Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality.Caspases as treatment targets in stroke and neurodegenerative diseases.Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.Mitochondrial dysfunction induced by nuclear poly(ADP-ribose) polymerase-1: a treatable cause of cell death in stroke.Mechanisms of gender-linked ischemic brain injury.E1B and E4 oncoproteins of adenovirus antagonize the effect of apoptosis inducing factorPotent neuroprotectants linked to bifunctional inhibitionSerine racemase deletion protects against cerebral ischemia and excitotoxicity.Neuroprotection in acute ischaemic stroke. II: Clinical potential.Sex differences in minocycline-induced neuroprotection after experimental strokeContributions of poly(ADP-ribose) polymerase-1 and -2 to nuclear translocation of apoptosis-inducing factor and injury from focal cerebral ischemia.NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death
P2860
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P2860
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
@en
type
label
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
@en
prefLabel
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
@en
P2093
P2860
P356
P1433
P1476
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
@en
P2093
Eliasson MJ
Traystman RJ
P2860
P2888
P304
P356
10.1038/NM1097-1089
P407
P577
1997-10-01T00:00:00Z