Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse.
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FGF9 can induce endochondral ossification in cranial mesenchyme.Fibroblast growth factor signaling in skeletal development and diseaseGenetic insights into the mechanisms of Fgf signalingFunctional diversity of fibroblast growth factors in bone formationEvidence that Fgf10 contributes to the skeletal and visceral defects of an Apert syndrome mouse modelEarly onset of craniosynostosis in an Apert mouse model reveals critical features of this pathologyGli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiationPresphenoidal synchondrosis fusion in DBA/2J mice.Craniofacial divergence by distinct prenatal growth patterns in Fgfr2 mutant miceThe old and new face of craniofacial research: How animal models inform human craniofacial genetic and clinical dataUnravelling the molecular control of calvarial suture fusion in children with craniosynostosis.Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice.Morphological comparison of the craniofacial phenotypes of mouse models expressing the Apert FGFR2 S252W mutation in neural crest- or mesoderm-derived tissues.Role of FGFR2-signaling in the pathogenesis of acne.Targeted sequencing in FGF/FGFR genes and association analysis of variants for mandibular prognathism.Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis.The balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development.FGF/FGFR signaling coordinates skull development by modulating magnitude of morphological integration: evidence from Apert syndrome mouse modelsBeyond the closed suture in apert syndrome mouse models: evidence of primary effects of FGFR2 signaling on facial shape at birth.Bent bone dysplasia syndrome reveals nucleolar activity for FGFR2 in ribosomal DNA transcription.Novel molecular pathways elicited by mutant FGFR2 may account for brain abnormalities in Apert syndrome.Surface landmark quantification of embryonic mouse craniofacial morphogenesis.Inhibited Wnt signaling causes age-dependent abnormalities in the bone matrix mineralization in the Apert syndrome FGFR2(S252W/+) miceRole of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models.Regulation of cranial morphogenesis and cell fate at the neural crest-mesoderm boundary by engrailed 1.Closing the Gap: Genetic and Genomic Continuum from Syndromic to Nonsyndromic Craniosynostoses.Bent bone dysplasia-FGFR2 type, a distinct skeletal disorder, has deficient canonical FGF signaling.Apert p.Ser252Trp mutation in FGFR2 alters osteogenic potential and gene expression of cranial periosteal cells.Binary Logistic Regression Analysis of Foramen Magnum Dimensions for Sex Determination.p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice.The effect of a Beare-Stevenson syndrome Fgfr2 Y394C mutation on early craniofacial bone volume and relative bone mineral density in mice.Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development.Drug-sensitive FGFR2 mutations in endometrial carcinomaFrom shape to cells: mouse models reveal mechanisms altering palate development in Apert syndromeAugmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice.Mesodermal expression of Fgfr2S252W is necessary and sufficient to induce craniosynostosis in a mouse model of Apert syndrome.Understanding craniosynostosis as a growth disorderFibroblast growth factor 10 plays a causative role in the tracheal cartilage defects in a mouse model of Apert syndrome.The FaceBase Consortium: a comprehensive resource for craniofacial researchers.EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis
P2860
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P2860
Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Abnormalities in cartilage and bone development in the Apert syndrome FGFR2
@nl
Abnormalities in cartilage and ...... syndrome FGFR2(+/S252W) mouse.
@en
type
label
Abnormalities in cartilage and bone development in the Apert syndrome FGFR2
@nl
Abnormalities in cartilage and ...... syndrome FGFR2(+/S252W) mouse.
@en
prefLabel
Abnormalities in cartilage and bone development in the Apert syndrome FGFR2
@nl
Abnormalities in cartilage and ...... syndrome FGFR2(+/S252W) mouse.
@en
P2093
P356
P1433
P1476
Abnormalities in cartilage and ...... syndrome FGFR2(+/S252W) mouse.
@en
P2093
Anthony J Iacovelli
Baktiar O Karim
Charles P Lerner
Cheryl A Hill
David L Huso
Jen M Leszl
Jennifer Elisseeff
Joan T Richtsmeier
Juanliang Cai
P304
P356
10.1242/DEV.01914
P407
P577
2005-06-23T00:00:00Z