about
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge aheadGlutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts.Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.Redox-Mediated Suberoylanilide Hydroxamic Acid Sensitivity in Breast Cancer.Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and AnoikisAcquired glucose sensitivity of k-ras transformed fibroblasts.Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodelingGlucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response.RAS and PKA pathways in cancer: new insight from transcriptional analysis.From cancer metabolism to new biomarkers and drug targets.New Insights into the Connection Between Histone Deacetylases, Cell Metabolism, and Cancer.Energy metabolism characterization of a novel cancer stem cell-like line 3AB-OS.Genetic and molecular characterization of the human osteosarcoma 3AB-OS cancer stem cell line: a possible model for studying osteosarcoma origin and stemness.Integrative transcriptional analysis between human and mouse cancer cells provides a common set of transformation associated genes.Transcriptional profiling of immortalized and K-ras-transformed mouse fibroblasts upon PKA stimulation by forskolin in low glucose availabilityMitochondrial complex I inhibitors and forced oxidative phosphorylation synergize in inducing cancer cell death.Analysis of mitochondrial metabolism in situ: Combining stable isotope labeling with selective permeabilization.Mitochondrial Complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells.Glucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response.Inhibition of the Hexosamine Biosynthetic Pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis.Expression of transforming K-Ras oncogene affects mitochondrial function and morphology in mouse fibroblasts.The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring.Design, Synthesis, and Preliminary Biological Evaluation of GlcNAc-6P Analogues for the Modulation of Phosphoacetylglucosamine Mutase 1 (AGM1/PGM3)Ras-dependent carbon metabolism and transformation in mouse fibroblastsHexosamine pathway inhibition overcomes pancreatic cancer resistance to gemcitabine through unfolded protein response and EGFR-Akt pathway modulationCentral metabolism of functionally heterogeneous mesenchymal stromal cells
P50
Q28397132-2017F093-77B4-4AA1-BCA9-588016704623Q33415058-7A26478F-3612-432F-A291-587393B3DE05Q34482056-7FB4D2D6-2C00-4CA7-B7D7-4E6D7EF84DA8Q35458543-E3D4167F-AEA8-48B3-97B7-50B8A4524B18Q35822102-43C30CEC-A734-4714-97DE-6908B718C1D9Q35957554-DECCF230-0466-42BD-8123-42574C0D48A3Q36018472-06C7AF03-1199-435C-805D-1A40A7141465Q36228895-D3F83B41-0520-4D00-9ED3-660B64A43082Q37062069-7B1DD60C-24C7-4E64-8BD2-5ECC19D18DC0Q37175499-5EDB8569-2F1C-4004-98C5-DFBBAC39D796Q37908507-BBAF509A-400C-4CF1-AE1D-36F3B37801F4Q38183888-5F37C5D8-D417-4555-A63B-BE771A3F2137Q39096563-77C62464-4D14-4F0B-893D-4A5764A9CAD7Q39248938-26B80EEE-A126-4CB6-B5EA-DEB8229E8E47Q39511204-72CB47D7-24E3-4325-901C-E7AE98F7305BQ39530105-FAF88C87-2502-4808-8227-F499D1AF613EQ40194409-3E271D00-95DD-4B52-A479-A44616783E89Q40405552-A66B9602-3921-4366-B9C0-0A0C5F9CBBB5Q43237277-57A5AF08-5B85-4B36-9B2A-E19043C72DBDQ45945447-8D15FB2F-2713-470D-9191-45CF4D94FF4CQ51743298-97832DE5-B509-4CE5-A54D-8D35D298F3D0Q53341827-3EA26E0A-4F91-493D-B035-6F3131BDD2C1Q55497180-C0BFABC2-BA88-4B29-A59B-5DD32D95FCCCQ60167239-FCB4F373-1C4E-4468-9869-77B8D864DF23Q61071496-0BA9232A-953D-46E2-B5BD-6BB624689324Q90814722-ED636D13-A6CD-4A96-8F5A-F2BC55789D62Q90975197-5BB94FF9-8CE6-4939-888A-7F214E8B3586
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Ferdinando Chiaradonna
@ast
Ferdinando Chiaradonna
@en
Ferdinando Chiaradonna
@es
Ferdinando Chiaradonna
@nl
Ferdinando Chiaradonna
@sl
type
label
Ferdinando Chiaradonna
@ast
Ferdinando Chiaradonna
@en
Ferdinando Chiaradonna
@es
Ferdinando Chiaradonna
@nl
Ferdinando Chiaradonna
@sl
prefLabel
Ferdinando Chiaradonna
@ast
Ferdinando Chiaradonna
@en
Ferdinando Chiaradonna
@es
Ferdinando Chiaradonna
@nl
Ferdinando Chiaradonna
@sl
P106
P21
P31
P496
0000-0001-8529-2732
P569
2000-01-01T00:00:00Z