Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth. - Wikidata - awgldk - TriplyDB

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

http://www.wikidata.org/entity/Q35458543

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Genetics and biology of pancreatic ductal adenocarcinoma Integration of Mitochondrial Targeting for Molecular Cancer Therapeutics Lipid metabolic reprogramming in cancer cells Cancer Metabolism and Drug Resistance Reviving Lonidamine and 6-Diazo-5-oxo-L-norleucine to Be Used in Combination for Metabolic Cancer Therapy Dysregulated metabolism contributes to oncogenesis Mitochondrial Energy Metabolism and Thyroid Cancers Redox control of glutamine utilization in cancer The emerging paradigm of network medicine in the study of human disease Targeting mitochondria metabolism for cancer therapy Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor Metabolic rewiring in melanoma Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symporters Metabolic consequences of oncogenic IDH mutations Metabolic pathways promoting cancer cell survival and growth Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia Analysis and interpretation of transcriptomic data obtained from extended Warburg effect genes in patients with clear cell renal cell carcinoma.1,25-dihydroxyvitamin D regulation of glucose metabolism in Harvey-ras transformed MCF10A human breast epithelial cells The complex landscape of pancreatic cancer metabolism From Krebs to clinic: glutamine metabolism to cancer therapy.Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism Capturing the metabolomic diversity of KRAS mutants in non-small-cell lung cancer cells.Pharmaco-metabolomics: an emerging "omics" tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets.Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?Computational strategies for a system-level understanding of metabolism.Interplay Between HGF/SF-Met-Ras Signaling, Tumor Metabolism and Blood Flow as a Potential Target for Breast Cancer Therapy Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein.Famine versus feast: understanding the metabolism of tumors in vivo.Drugging the undruggable RAS: Mission possible?Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.IL4 receptor α mediates enhanced glucose and glutamine metabolism to support breast cancer growth.13C isotope-assisted methods for quantifying glutamine metabolism in cancer cells.2-Substituted Nγ-glutamylanilides as novel probes of ASCT2 with improved potency.Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect.Altered glucose metabolism in Harvey-ras transformed MCF10A cells Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.2-Amino-4-bis(aryloxybenzyl)aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport.Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells.Comparing Alzheimer's and Parkinson's diseases networks using graph communities structure

P2860

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P2860

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

http://www.wikidata.org/entity/Q35458543

description

2011 nî lūn-bûn

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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

@ast

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

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type

label

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

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Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

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prefLabel

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

@ast

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

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Molecular Systems Biology

P1476

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

@en

P2093

Christian M Metallo

http://www.w3.org/2001/XMLSchema#string

Daniela Gaglio

http://www.w3.org/2001/XMLSchema#string

Gregory Stephanopoulos

http://www.w3.org/2001/XMLSchema#string

Karsten Hiller

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Lara Sala Danna

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Paulo A Gameiro

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P2860

Identification of small molecule inhibitors of pyruvate kinase M2

The Hallmarks of Cancer

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

Cancer systems biology: a network modeling perspective

On the Origin of Cancer Cells

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

Systematic variation in gene expression patterns in human cancer cell lines

Targeting RAS signalling pathways in cancer therapy

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523

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10.1038/MSB.2011.56

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7

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Lilia Alberghina

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51576540

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21847114

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3202795

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