Dissociation of demyelination and viral clearance in congenitally immunodeficient mice infected with murine coronavirus JHM.
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MicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic diseaseDemyelination determinants map to the spike glycoprotein gene of coronavirus mouse hepatitis virusInfection with cytotoxic T-lymphocyte escape mutants results in increased mortality and growth retardation in mice infected with a neurotropic coronavirus.Viral expression of CCL2 is sufficient to induce demyelination in RAG1-/- mice infected with a neurotropic coronavirus.A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelinationCoronavirus-induced demyelination occurs in the absence of inducible nitric oxide synthaseDepletion of blood-borne macrophages does not reduce demyelination in mice infected with a neurotropic coronavirus.Macrophage infiltration, but not apoptosis, is correlated with immune-mediated demyelination following murine infection with a neurotropic coronavirus.Axonal damage is T cell mediated and occurs concomitantly with demyelination in mice infected with a neurotropic coronavirus.High-magnitude, virus-specific CD4 T-cell response in the central nervous system of coronavirus-infected mice.Important roles for gamma interferon and NKG2D in gammadelta T-cell-induced demyelination in T-cell receptor beta-deficient mice infected with a coronavirusA severe acute respiratory syndrome-associated coronavirus-specific protein enhances virulence of an attenuated murine coronavirusA mechanism of virus-induced demyelination.Pathogenesis of murine coronavirus in the central nervous system.CD4 T-cell-mediated demyelination is increased in the absence of gamma interferon in mice infected with mouse hepatitis virus.Bystander CD8 T-cell-mediated demyelination is interferon-gamma-dependent in a coronavirus model of multiple sclerosis.Virus-specific antibody, in the absence of T cells, mediates demyelination in mice infected with a neurotropic coronavirusInhibition of interferon-gamma signaling in oligodendroglia delays coronavirus clearance without altering demyelination.Pathogenic role for virus-specific CD4 T cells in mice with coronavirus-induced acute encephalitis.In vivo expression of major histocompatibility complex molecules on oligodendrocytes and neurons during viral infectionDifferential induction of proinflammatory cytokines in primary mouse astrocytes and microglia by coronavirus infectionVirus-induced demyelination in nude mice is mediated by gamma delta T cells.Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis.Cytotoxic T-cell-resistant variants arise at early times after infection in C57BL/6 but not in SCID mice infected with a neurotropic coronavirus.CXCR2 signaling and host defense following coronavirus-induced encephalomyelitis.Induction of caspase-dependent apoptosis in cultured rat oligodendrocytes by murine coronavirus is mediated during cell entry and does not require virus replication.Complete protection against severe acute respiratory syndrome coronavirus-mediated lethal respiratory disease in aged mice by immunization with a mouse-adapted virus lacking E protein.Generation of a protective T-cell response following coronavirus infection of the central nervous system is not dependent on IL-12/23 signaling.Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cellsMouse hepatitis virus infection of the CNS: a model for defense, disease, and repair.Protective and pathologic roles of the immune response to mouse hepatitis virus type 1: implications for severe acute respiratory syndrome.Expression of cellular oncogene Bcl-xL prevents coronavirus-induced cell death and converts acute infection to persistent infection in progenitor rat oligodendrocytesMurine coronavirus neuropathogenesis: determinants of virulence.Roles of regulatory T cells and IL-10 in virus-induced demyelination.MicroRNA 155 and viral-induced neuroinflammation.Microglia are required for protection against lethal coronavirus encephalitis in mice.
P2860
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P2860
Dissociation of demyelination and viral clearance in congenitally immunodeficient mice infected with murine coronavirus JHM.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Dissociation of demyelination ...... d with murine coronavirus JHM.
@en
Dissociation of demyelination ...... d with murine coronavirus JHM.
@nl
type
label
Dissociation of demyelination ...... d with murine coronavirus JHM.
@en
Dissociation of demyelination ...... d with murine coronavirus JHM.
@nl
prefLabel
Dissociation of demyelination ...... d with murine coronavirus JHM.
@en
Dissociation of demyelination ...... d with murine coronavirus JHM.
@nl
P1476
Dissociation of demyelination ...... d with murine coronavirus JHM.
@en
P2093
Fleming JO
Houtman JJ
P304
P577
1996-04-01T00:00:00Z