Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinases.
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Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptorsPhosphoinositides: tiny lipids with giant impact on cell regulationSTT4 is an essential phosphatidylinositol 4-kinase that is a target of wortmannin in Saccharomyces cerevisiae.A novel family of phosphatidylinositol 4-kinases conserved from yeast to humansDistinct Golgi populations of phosphatidylinositol 4-phosphate regulated by phosphatidylinositol 4-kinasesA specific role of phosphatidylinositol 3-kinase gamma. A regulation of autonomic Ca(2)+ oscillations in cardiac cellsActivation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphateGolgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current.Kinetic analysis of receptor-activated phosphoinositide turnoverRegulated phosphorylation of 40S ribosomal protein S6 in root tips of maize.Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole.Complex functions of phosphatidylinositol 4,5-bisphosphate in regulation of TRPC5 cation channels.Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesisRac regulates integrin-mediated spreading and increased adhesion of T lymphocytes.Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry.The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins.A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1.Activation of Akt by the bacterial inositol phosphatase, SopB, is wortmannin insensitive.Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments.Signaling microdomains regulate inositol 1,4,5-trisphosphate-mediated intracellular calcium transients in cultured neuronsCombined phosphoinositide and Ca2+ signals mediating receptor specificity toward neuronal Ca2+ channels.A human class II MHC-derived peptide antagonizes phosphatidylinositol 3-kinase to block IL-2 signaling.A novel fluorescence-based biosynthetic trafficking method provides pharmacologic evidence that PI4-kinase IIIα is important for protein trafficking from the endoplasmic reticulum to the plasma membraneDetection and manipulation of phosphoinositides.Genetic and functional studies of phosphatidyl-inositol 4-kinase type IIIαVisualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools.Electrostatic interaction of internal Mg2+ with membrane PIP2 Seen with KCNQ K+ channels.BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation.Isolation and molecular cloning of wortmannin-sensitive bovine type III phosphatidylinositol 4-kinases.A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ.Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides.Crucial role of phosphatidylinositol 4-kinase IIIalpha in development of zebrafish pectoral fin is linked to phosphoinositide 3-kinase and FGF signaling.Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels.Trafficking of Acetyl-C16-Ceramide-NBD with Long-Term Stability and No Cytotoxicity into the Golgi Complex.Dynamic sensitivity of ATP-sensitive K(+) channels to ATP.Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation.Phosphoinositides regulate membrane-dependent actin assembly by latex bead phagosomes.Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated signalling in single neurons.Exploring the specificity of the PI3K family inhibitor LY294002.Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
P2860
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P2860
Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinases.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Characterization of a soluble ...... phosphatidylinositol kinases.
@en
Characterization of a soluble ...... phosphatidylinositol kinases.
@nl
type
label
Characterization of a soluble ...... phosphatidylinositol kinases.
@en
Characterization of a soluble ...... phosphatidylinositol kinases.
@nl
prefLabel
Characterization of a soluble ...... phosphatidylinositol kinases.
@en
Characterization of a soluble ...... phosphatidylinositol kinases.
@nl
P2093
P356
P1433
P1476
Characterization of a soluble ...... phosphatidylinositol kinases.
@en
P2093
P304
P356
10.1021/BI9517493
P407
P50
P577
1996-03-01T00:00:00Z