The catalytically active copper-amyloid-Beta state: coordination site responsible for reactive oxygen species production.
about
Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.The Necessity of Having a Tetradentate Ligand to Extract Copper(II) Ions from Amyloids.Few-layer bismuth selenides exfoliated by hemin inhibit amyloid-β1-42 fibril formation.Copper(I/II), α/β-Synuclein and Amyloid-β: Menage à Trois?Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing.Short peptides self-assemble to produce catalytic amyloids.Biological metals and metal-targeting compounds in major neurodegenerative diseases.Receptor-mediated toxicity of human amylin fragment aggregated by short- and long-term incubations with copper ions.Co-assembly of polyoxometalates and peptides towards biological applications.Histidine availability is decisive in ROS-mediated cytotoxicity of copper complexes of Aβ1-16 peptide.Ultraviolet light triggers the conversion of Cu2+-bound Aβ42 aggregates into cytotoxic species in a copper chelation-independent manner.Implications of peptide assemblies in amyloid diseases.Short Self-Assembling Peptides Are Able to Bind to Copper and Activate OxygenKinetic Analysis Reveals the Identity of Aβ-Metal Complex Responsible for the Initial Aggregation of Aβ in the Synapse.Identification of key structural features of the elusive Cu-Aβ complex that generates ROS in Alzheimer's disease.The double-edged role of copper in the fate of amyloid beta in the presence of anti-oxidants.Effect of methionine-35 oxidation on the aggregation of amyloid-β peptide.Oxidative stress and the amyloid beta peptide in Alzheimer's disease.A Trishistidine Pseudopeptide with Ability to Remove Both CuΙ and CuΙΙ from the Amyloid-β Peptide and to Stop the Associated ROS Formation.Metal-catalyzed oxidation of Aβ and the resulting reorganization of Cu binding sites promote ROS production.Is ascorbate Dr Jekyll or Mr Hyde in the Cu(Aβ) mediated oxidative stress linked to Alzheimer's disease?On the generation of OH(·) radical species from H2O2 by Cu(I) amyloid beta peptide model complexes: a DFT investigation.Free Superoxide is an Intermediate in the Production of H2O2 by Copper(I)-Aβ Peptide and O2.Copper-Aβ Peptides and Oxidation of Catecholic Substrates: Reactivity and Endogenous Peptide Damage.Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids.Characterization of new specific copper chelators as potential drugs for the treatment of Alzheimer's disease.A metallo pro-drug to target Cu(II) in the context of Alzheimer's disease.Ascorbate Oxidation by Cu(Amyloid-β) Complexes: Determination of the Intrinsic Rate as a Function of Alterations in the Peptide Sequence Revealing Key Residues for Reactive Oxygen Species Production.Catalytic Amyloid Fibrils That Bind Copper to Activate Oxygen.Copper Redox Cycling Inhibits Aβ Fibre Formation and Promotes Fibre Fragmentation, while Generating a Dityrosine Aβ DimerCopper in Alzheimer’s disease: Implications in amyloid aggregation and neurotoxicity
P2860
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P2860
The catalytically active copper-amyloid-Beta state: coordination site responsible for reactive oxygen species production.
description
2013 nî lūn-bûn
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2013年の論文
@ja
2013年学术文章
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2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
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2013年學術文章
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name
The catalytically active coppe ...... ive oxygen species production.
@en
The catalytically active coppe ...... ive oxygen species production.
@nl
type
label
The catalytically active coppe ...... ive oxygen species production.
@en
The catalytically active coppe ...... ive oxygen species production.
@nl
prefLabel
The catalytically active coppe ...... ive oxygen species production.
@en
The catalytically active coppe ...... ive oxygen species production.
@nl
P2093
P2860
P356
P1476
The catalytically active coppe ...... ive oxygen species production.
@en
P2093
Christelle Hureau
Fabrice Collin
Françoise Nepveu
Laure-Estelle Cassagnes
Vincent Hervé
P2860
P304
11110-11113
P356
10.1002/ANIE.201305372
P407
P577
2013-09-03T00:00:00Z