Correlation of levels of folded recombinant p53 in escherichia coli with thermodynamic stability in vitro.
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Determining biophysical protein stability in lysates by a fast proteolysis assay, FASTppTargeted rescue of a destabilized mutant of p53 by an in silico screened drugGenetic and Structural Characterization of an L201P Global Suppressor Substitution in TEM-1 β-LactamaseStabilising the DNA-binding domain of p53 by rational design of its hydrophobic coreMetamorphic proteins mediate evolutionary transitions of structureInteraction of p53 with the CCT complex promotes protein folding and wild-type p53 activityMissense mutation Lys18Asn in dystrophin that triggers X-linked dilated cardiomyopathy decreases protein stability, increases protein unfolding, and perturbs protein structure, but does not affect protein function.SDM--a server for predicting effects of mutations on protein stability and malfunction.A structural systems biology approach for quantifying the systemic consequences of missense mutations in proteins.Missense mutations in dystrophin that trigger muscular dystrophy decrease protein stability and lead to cross-beta aggregates.Biophysics of protein evolution and evolutionary protein biophysicsOn the molecular basis of D-bifunctional protein deficiency type III.Protein folding in the cell: challenges and progress.In silico analysis of functional single nucleotide polymorphisms in the human TRIM22 geneGlobal analysis of protein folding thermodynamics for disease state characterizationLarge-scale experimental studies show unexpected amino acid effects on protein expression and solubility in vivo in E. coli.Structural insights into the folding defects of oncogenic pVHL lead to correction of its function in vitro.The tumor suppressor p53: from structures to drug discovery.Modulating protein stability - directed evolution strategies for improved protein function.Dynamics and constraints of enzyme evolution.Rapid perturbation of free-energy landscapes: from in vitro to in vivo.Chaperonins fight aminoglycoside-induced protein misfolding and promote short-term tolerance in Escherichia coli.Effects of stability on the biological function of p53.Conformational Stability and Pathogenic Misfolding of the Integral Membrane Protein PMP22.Folding of a cyclin box: linking multitarget binding to marginal stability, oligomerization, and aggregation of the retinoblastoma tumor suppressor AB pocket domainCytosolic selection systems to study protein stability.Optimizing protein stability in vivoThermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.Integration of host strain bioengineering and bioprocess development using ultra-scale down studies to select the optimum combination: an antibody fragment primary recovery case study.Towards the classification of DYT6 dystonia mutants in the DNA-binding domain of THAP1.A comprehensive biophysical description of pairwise epistasis throughout an entire protein domain.Discovery of Age-Related Protein Folding Stability Differences in the Mouse Brain Proteome.Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer.Identification and in silico analysis of functional SNPs of human TAGAP protein: A comprehensive study.The mutational status of p53 can influence its recognition by human T-cells.Path-based approach to random walks on networks characterizes how proteins evolve new functions.Accurate prediction of functional, structural, and stability changes in PITX2 mutations using in silico bioinformatics algorithms.Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insightsThioflavin-S staining coupled to flow cytometry. A screening tool to detect in vivo protein aggregation
P2860
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P2860
Correlation of levels of folded recombinant p53 in escherichia coli with thermodynamic stability in vitro.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Correlation of levels of folde ...... rmodynamic stability in vitro.
@en
Correlation of levels of folde ...... rmodynamic stability in vitro.
@nl
type
label
Correlation of levels of folde ...... rmodynamic stability in vitro.
@en
Correlation of levels of folde ...... rmodynamic stability in vitro.
@nl
prefLabel
Correlation of levels of folde ...... rmodynamic stability in vitro.
@en
Correlation of levels of folde ...... rmodynamic stability in vitro.
@nl
P50
P1476
Correlation of levels of folde ...... rmodynamic stability in vitro.
@en
P2093
Hwee Ching Ang
Sebastian Mayer
P304
P356
10.1016/J.JMB.2007.06.044
P407
P577
2007-06-22T00:00:00Z