A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor.
about
The 5-HT3B subunit is a major determinant of serotonin-receptor functionImportance of Arg-219 for correct biogenesis of alpha 1 homooligomeric glycine receptorsX-ray structure of a pentameric ligand-gated ion channel in an apparently open conformationStructural basis for ion permeation mechanism in pentameric ligand-gated ion channelsNeuronal nicotinic receptors: from protein structure to functionThe atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channelsTryptophan substitutions at lipid-exposed positions of the gamma M3 transmembrane domain increase the macroscopic ionic current response of the Torpedo californica nicotinic acetylcholine receptorCyanotriphenylborate: subtype-specific blocker of glycine receptor chloride channelsResidues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomersCloning, expression and modulation of a mouse NMDA receptor subunitTracking the molecular evolution of calcium permeability in a nicotinic acetylcholine receptorHomologous mutations on different subunits cause unequal but additive effects on n-alcohol block in the nicotinic receptor poreM2 pore mutations convert the glycine receptor channel from being anion- to cation-selective.A model of the closed form of the nicotinic acetylcholine receptor m2 channel pore.Nicotinic acetylcholine receptor and the structural basis of neuromuscular transmission: insights from Torpedo postsynaptic membranesIn glycine and GABA(A) channels, different subunits contribute asymmetrically to channel conductance via residues in the extracellular domain.Structural effects of quinacrine binding in the open channel of the acetylcholine receptor.The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis.Charge selectivity of the Cys-loop family of ligand-gated ion channels.State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor. Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the alpha subunit.The intrinsic electrostatic potential and the intermediate ring of charge in the acetylcholine receptor channel.Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit.Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor.Kinked-helices model of the nicotinic acetylcholine receptor ion channel and its complexes with blockers: simulation by the Monte Carlo minimization method.Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors.Ion channels: molecular basis of ion selectivity.The investigation of congenital myasthenic syndromes.Mutations at the GABA receptor selectivity filter: a possible role for effective charges.Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A).Molecular aspects of ion permeation through channels.Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor.Assigning functions to residues in the acetylcholine receptor channel region (review).Molecular modelling of the interactions of carbamazepine and a nicotinic receptor involved in the autosomal dominant nocturnal frontal lobe epilepsyElectrostatics of a simple membrane model using Green's functions formalism.Design, synthesis and functional characterization of a pentameric channel protein that mimics the presumed pore structure of the nicotinic cholinergic receptor.A negative charge in the M2 transmembrane segment of the neuronal alpha 7 acetylcholine receptor increases permeability to divalent cations.Nicotinic acetylcholine receptors (nAChRs) at zebrafish red and white muscle show different properties during development.Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II.
P2860
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P2860
A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh-hant
name
A ring of uncharged polar amin ...... otinic acetylcholine receptor.
@en
A ring of uncharged polar amin ...... otinic acetylcholine receptor.
@nl
type
label
A ring of uncharged polar amin ...... otinic acetylcholine receptor.
@en
A ring of uncharged polar amin ...... otinic acetylcholine receptor.
@nl
prefLabel
A ring of uncharged polar amin ...... otinic acetylcholine receptor.
@en
A ring of uncharged polar amin ...... otinic acetylcholine receptor.
@nl
P2093
P2860
P1433
P1476
A ring of uncharged polar amin ...... otinic acetylcholine receptor.
@en
P2093
P2860
P304
P356
10.1016/0014-5793(91)81068-J
P407
P577
1991-09-01T00:00:00Z