Inhibition of cardiac delayed rectifier K+ current by overexpression of the long-QT syndrome HERG G628S mutation in transgenic mice.
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Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f)Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotypeZebrafish model for human long QT syndromeInherited long QT syndromes: a paradigm for understanding arrhythmogenesis.Mouse models of long QT syndrome.Zebrafish as a model for long QT syndrome: the evidence and the means of manipulating zebrafish gene expression.MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult heartsElectrophysiological alterations in a murine model of chronic coxsackievirus B3 myocarditisProperties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes.Arrhythmia phenotype during fetal life suggests long-QT syndrome genotype: risk stratification of perinatal long-QT syndrome.Isoform-specific dominant-negative effects associated with hERG1 G628S mutation in long QT syndrome.Selective knockout of mouse ERG1 B potassium channel eliminates I(Kr) in adult ventricular myocytes and elicits episodes of abrupt sinus bradycardia.The ionic bases of the action potential in isolated mouse cardiac Purkinje cellDistinct gene-specific mechanisms of arrhythmia revealed by cardiac gene transfer of two long QT disease genes, HERG and KCNE1.Nonlinearity between action potential alternans and restitution, which both predict ventricular arrhythmic properties in Scn5a+/- and wild-type murine heartsRapid genetic algorithm optimization of a mouse computational model: benefits for anthropomorphization of neonatal mouse cardiomyocytesEffects of potassium channel openers in the isolated perfused hypokalaemic murine heart.HERG potassium channels are more frequently expressed in human endometrial cancer as compared to non-cancerous endometriumMouse models of human arrhythmia syndromes.Action potential wavelength restitution predicts alternans and arrhythmia in murine Scn5a(+/-) hearts.Characterization of hERG1 channel role in mouse colorectal carcinogenesis.On the emerging role of rabbit as human disease model and the instrumental role of novel transgenic tools.Cardiac electrophysiology in mice: a matter of size.miRNA in the regulation of ion channel/transporter expression.Murine Electrophysiological Models of Cardiac Arrhythmogenesis.Species-Dependent Mechanisms of Cardiac Arrhythmia: A Cellular Focus.Cardiac channelopathies: from men to mice.Blockade of permeation by potassium but normal gating of the G628S nonconducting hERG channel mutant.Regional variations in action potential alternans in isolated murine Scn5a (+/-) hearts during dynamic pacing.Correlation of repolarization of ventricular monophasic action potential with ECG in the murine heart.Regional upregulation of Kv2.1-encoded current, IK,slow2, in Kv1DN mice is abolished by crossbreeding with Kv2DN mice.The electrophysiological properties of spontaneously beating pacemaker cells isolated from mouse sinoatrial node.A rapidly activating delayed rectifier K+ current regulates pacemaker activity in adult mouse sinoatrial node cells.Functional properties of K+ currents in adult mouse ventricular myocytes.Mechanisms of ventricular arrhythmogenesis in mice following targeted disruption of KCNE1 modelling long QT syndrome 5.Beat-to-beat repolarization variability in ventricular myocytes and its suppression by electrical coupling.Single-channel recordings of a rapid delayed rectifier current in adult mouse ventricular myocytes: basic properties and effects of divalent cations.Kv11.1 channel subunit composition includes MinK and varies developmentally in mouse cardiac muscle.Age-dependent response of the electrocardiogram to K(+) channel blockers in mice.
P2860
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P2860
Inhibition of cardiac delayed rectifier K+ current by overexpression of the long-QT syndrome HERG G628S mutation in transgenic mice.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Inhibition of cardiac delayed ...... S mutation in transgenic mice.
@en
Inhibition of cardiac delayed ...... S mutation in transgenic mice.
@nl
type
label
Inhibition of cardiac delayed ...... S mutation in transgenic mice.
@en
Inhibition of cardiac delayed ...... S mutation in transgenic mice.
@nl
prefLabel
Inhibition of cardiac delayed ...... S mutation in transgenic mice.
@en
Inhibition of cardiac delayed ...... S mutation in transgenic mice.
@nl
P2093
P356
P1433
P1476
Inhibition of cardiac delayed ...... S mutation in transgenic mice.
@en
P2093
B Nieuwenhuijsen
L J DeGennaro
T J Colatsky
T M Argentieri
T R Bridal
P304
P356
10.1161/01.RES.83.6.668
P577
1998-09-01T00:00:00Z