Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.
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Hematopoietic stem cell development, niches, and signaling pathwaysSoluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesisMicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiationPh+/VE-cadherin+ identifies a stem cell like population of acute lymphoblastic leukemia sustained by bone marrow niche cellsWnt signaling promotes hematoendothelial cell development from human embryonic stem cellsA CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repairWnt signaling: the good and the badKlotho and agingHematopoietic fingerprints: an expression database of stem cells and their progenyKlotho in cardiovascular disease: Current and future perspectivesThe Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem CellsHematopoietic stem cell niche maintenance during homeostasis and regenerationWnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentChallenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?A critical role for Apc in hematopoietic stem and progenitor cell survivalHematopoietic stem cell: self-renewal versus differentiationHematopoiesis: an evolving paradigm for stem cell biologyActivation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cellsHedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning.Perturbation of single hematopoietic stem cell fates in artificial nichesId1 restrains p21 expression to control endothelial progenitor cell formation.MicroRNA-29 induces cellular senescence in aging muscle through multiple signaling pathwaysLoss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration.Angelica Sinensis Polysaccharide Prevents Hematopoietic Stem Cells Senescence in D-Galactose-Induced Aging Mouse Model.Integrated genetic approaches identify the molecular mechanisms of Sox4 in early B-cell development: intricate roles for RAG1/2 and CK1ε.Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy.The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS.Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycleWnt/β-catenin signaling induces the aging of mesenchymal stem cells through the DNA damage response and the p53/p21 pathway.Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.Decreased SFRP2 expression is associated with intermediate and poor karyotypes in de novo acute myeloid leukemiamTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.Signalling pathways that control vertebrate haematopoietic stem cell specification.Wnt-related molecules and signaling pathway equilibrium in hematopoiesis.Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specificationWnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.Maintenance of HSC by Wnt5a secreting AGM-derived stromal cell line.Implications of Klotho in vascular health and disease.Heterogeneous sensitivity of human acute myeloid leukemia to β-catenin down-modulation.
P2860
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P2860
Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Activation of the canonical Wn ...... lineage differentiation block.
@en
Activation of the canonical Wn ...... lineage differentiation block.
@nl
type
label
Activation of the canonical Wn ...... lineage differentiation block.
@en
Activation of the canonical Wn ...... lineage differentiation block.
@nl
prefLabel
Activation of the canonical Wn ...... lineage differentiation block.
@en
Activation of the canonical Wn ...... lineage differentiation block.
@nl
P2860
P50
P356
P1433
P1476
Activation of the canonical Wn ...... lineage differentiation block.
@en
P2093
Claus Nerlov
Kristina Anderson
P2860
P304
P356
10.1038/NI1381
P407
P577
2006-09-03T00:00:00Z