Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint.
about
The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions.CAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment.Murine CENP-F regulates centrosomal microtubule nucleation and interacts with Hook2 at the centrosomeThree wise centromere functions: see no error, hear no break, speak no delayLoss of CENP-F results in distinct microtubule-related defects without chromosomal abnormalities.Centromere protein F includes two sites that couple efficiently to depolymerizing microtubulesSlk19 clusters kinetochores and facilitates chromosome bipolar attachment.The Toxoplasma gondii kinetochore is required for centrosome association with the centrocone (spindle pole)Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase.Genetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans.Studies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesionCharacterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbationsProbing cell-division phenotype space and Polo-like kinase function using small molecules.GSK-3 inhibitors induce chromosome instability.Rab5a is required for spindle length control and kinetochore-microtubule attachment during meiosis in oocytesPrognostic significance and therapeutic implications of centromere protein F expression in human nasopharyngeal carcinomaSmall GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochoresMitosis, microtubule dynamics and the evolution of kinesins.The enhancement of pericentromeric cohesin association by conserved kinetochore components promotes high-fidelity chromosome segregation and is sensitive to microtubule-based tensionControl of regional decidualization in implantation: Role of FoxM1 downstream of Hoxa10 and cyclin D3Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells.How to build a centromere: from centromeric and pericentromeric chromatin to kinetochore assembly.CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancerMechanisms of chromosomal instability.Differential gene expression by endothelial cells under positive and negative streamwise gradients of high wall shear stress.Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay.The microtubule binding properties of CENP-E's C-terminus and CENP-F.Mechanisms of Chromosome Congression during Mitosis.Regulatory mechanisms of kinetochore-microtubule interaction in mitosis.Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint.Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancyPrognostic relevance and therapeutic implications of centromere protein F expression in patients with esophageal squamous cell carcinoma.Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity.Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F.The kinetochore protein Cenp-F is a potential novel target for zoledronic acid in breast cancer cells.ASURA (PHB2) Is Required for Kinetochore Assembly and Subsequent Chromosome Congression.Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts.Kinetochore Malfunction in Human Pathologies.A novel function of Rab5 in mitosisSynthetic lethal interactions identify phenotypic "interologs" of the spindle assembly checkpoint components.
P2860
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P2860
Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Silencing Cenp-F weakens centr ...... ivates the spindle checkpoint.
@en
Silencing Cenp-F weakens centr ...... ivates the spindle checkpoint.
@nl
type
label
Silencing Cenp-F weakens centr ...... ivates the spindle checkpoint.
@en
Silencing Cenp-F weakens centr ...... ivates the spindle checkpoint.
@nl
prefLabel
Silencing Cenp-F weakens centr ...... ivates the spindle checkpoint.
@en
Silencing Cenp-F weakens centr ...... ivates the spindle checkpoint.
@nl
P2093
P50
P356
P1476
Silencing Cenp-F weakens centr ...... tivates the spindle checkpoint
@en
P2093
Deema Hussein
Mailys A S Vergnolle
Sarah V Holt
P304
P356
10.1242/JCS.02614
P407
P577
2005-10-01T00:00:00Z