Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
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Francis Crick's legacy for neuroscience: between the alpha and the OmegaRecombinant human insulin-like growth factor I (rhIGF-I) for the treatment of amyotrophic lateral sclerosis/motor neuron diseaseRecombinant human insulin-like growth factor I (rhIGF-I) for amyotrophic lateral sclerosis/motor neuron diseaseIntramuscular viral delivery of paraplegin rescues peripheral axonopathy in a model of hereditary spastic paraplegiaUpregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegenerationInsulin-like growth factor-I for the treatment of amyotrophic lateral sclerosisDelivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy.Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosisAdeno Associated Viral Vector Delivered RNAi for Gene Therapy of SOD1 Amyotrophic Lateral SclerosisFrom animal models to human disease: a genetic approach for personalized medicine in ALSDevelopmental Dynamics of Rett SyndromeMechanisms of Muscle Denervation in Aging: Insights from a Mouse Model of Amyotrophic Lateral SclerosisRetrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and diseaseTrophic factors as modulators of motor neuron physiology and survival: implications for ALS therapyMicroglia centered pathogenesis in ALS: insights in cell interconnectivityCMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.Increased androgenic sensitivity in the hind limb muscular system marks the evolution of a derived gestural displayImpaired axonal transport in motor neurons correlates with clinical prion diseaseAxonal transport of AAV9 in nonhuman primate brain.Postnatal muscle modification by myogenic factors modulates neuropathology and survival in an ALS mouse modelNon-Viral Nucleic Acid Delivery Strategies to the Central Nervous SystemThe effects of testosterone and insulin-like growth factor 1 on motor system form and functionEmerging drugs for sarcopenia: age-related muscle wastingALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the diseaseOrganically modified silica nanoparticles are biocompatible and can be targeted to neurons in vivoAblation of proliferating cells in the CNS exacerbates motor neuron disease caused by mutant superoxide dismutaseAls2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalitiesIGFBP-5 regulates muscle cell differentiation by binding to IGF-II and switching on the IGF-II auto-regulation loopHormones and the neuromuscular control of courtship in the golden-collared manakin (Manacus vitellinus).A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosisMicrobubbles and ultrasound increase intraventricular polyplex gene transfer to the brain.Peripheral androgen receptors sustain the acrobatics and fine motor skill of elaborate male courtship.Research Resource: Hormones, Genes, and Athleticism: Effect of Androgens on the Avian Muscular TranscriptomeThe role of microglia in brain maintenance: implications for Rett syndrome.Cortical area size dictates performance at modality-specific behaviors.Expansive gene transfer in the rat CNS rapidly produces amyotrophic lateral sclerosis relevant sequelae when TDP-43 is overexpressed.Viral delivery of antioxidant genes as a therapeutic strategy in experimental models of amyotrophic lateral sclerosis.Human gene therapy and imaging in neurological diseases.No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse model.Neuronal affinity of a C7C loop peptide identified through phage display.
P2860
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P2860
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
@en
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
@nl
type
label
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
@en
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
@nl
prefLabel
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
@en
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
@nl
P2093
P356
P1433
P1476
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
@en
P2093
Brian K Kaspar
Fred H Gage
Jeffrey D Rothstein
Jerònia Lladó
Nushin Sherkat
P304
P356
10.1126/SCIENCE.1086137
P407
P577
2003-08-01T00:00:00Z