TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation.
about
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria MarburgvirusTIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactionsImmune Regulation and Antitumor Effect of TIM-1TIM polymorphisms--genetics and functionPhosphatidylserine receptors: enhancers of enveloped virus entry and infectionGenome-wide association study of susceptibility to infection by Mycobacterium avium subspecies paratuberculosis in Holstein cattleStructures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine BindsG-protein-coupled receptors and asthma endophenotypes: the cysteinyl leukotriene system in perspectiveApoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivityTIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injuryT cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinaseApoptotic cell recognition receptors and scavenger receptors.The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis.T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice.Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophagesTim-2 regulates T helper type 2 responses and autoimmunityTIM-1 glycoprotein binds the adhesion receptor P-selectin and mediates T cell trafficking during inflammation and autoimmunityFragile TIM-4-expressing tissue resident macrophages are migratory and immunoregulatory.Suppression of allograft rejection by Tim-1-Fc through cross-linking with a novel Tim-1 binding partner on T cells.Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury.T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation.TIM-4 expressed on APCs induces T cell expansion and survival.Costimulatory pathways in transplantation.T-cell immunoglobulin mucin-3 determines severity of liver ischemia/reperfusion injury in mice in a TLR4-dependent mannerSequence, structure, function, immunity: structural genomics of costimulation.Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53Creating transplant tolerance by taming adverse intragraft innate immunity.The TIM-1:TIM-4 pathway enhances renal ischemia-reperfusion injuryThe emerging role of T cell immunoglobulin mucin-1 in the mechanism of liver ischemia and reperfusion injury in the mouseTIM4 Regulates the Anti-Islet Th2 Alloimmune ResponseTim-1 stimulation of dendritic cells regulates the balance between effector and regulatory T cells.Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation.TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells.Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice.Intestinal epithelial barrier dysfunction in food hypersensitivity.Glioma-derived T cell immunoglobulin- and mucin domain-containing molecule-4 (TIM4) contributes to tumor toleranceT-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury.Tim-4 Inhibits NO Generation by Murine Macrophages.HAVCR1 gene haplotypes and infection by different viral hepatitis C virus genotypes
P2860
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P2860
TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
TIM-4 is the ligand for TIM-1, ...... egulates T cell proliferation.
@en
TIM-4 is the ligand for TIM-1, ...... egulates T cell proliferation.
@nl
type
label
TIM-4 is the ligand for TIM-1, ...... egulates T cell proliferation.
@en
TIM-4 is the ligand for TIM-1, ...... egulates T cell proliferation.
@nl
prefLabel
TIM-4 is the ligand for TIM-1, ...... egulates T cell proliferation.
@en
TIM-4 is the ligand for TIM-1, ...... egulates T cell proliferation.
@nl
P2093
P2860
P356
P1433
P1476
TIM-4 is the ligand for TIM-1, ...... egulates T cell proliferation.
@en
P2093
Dale T Umetsu
David Schlesinger
Hanspeter Waldner
James Kenny
Jennifer Hartt Meyers
Rosemarie H DeKruyff
Sarah E Umetsu
Sumone Chakravarti
Terry B Strom
Vijay K Kuchroo
P2860
P304
P356
10.1038/NI1185
P407
P577
2005-03-27T00:00:00Z