Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.
about
A novel protease-docking function of integrin at invadopodiaForm and function: the laminin family of heterotrimersPhosphorylated alpha-actinin and protein-tyrosine phosphatase 1B coregulate the disassembly of the focal adhesion kinase x Src complex and promote cell migrationFilamin binds to the cytoplasmic domain of the beta1-integrin. Identification of amino acids responsible for this interactionp190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linkingBeta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunitIdentification of p130Cas as a mediator of focal adhesion kinase-promoted cell migrationLeukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeletonMonocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteinsThe MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.Tensin1 and a previously undocumented family member, tensin2, positively regulate cell migrationSyndecans: multifunctional cell-surface co-receptorscDNA cloning reveals two mouse beta5 integrin transcripts distinct in cytoplasmic domains as a result of alternative splicingA region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-associationIntegrin alpha 4 cysteines 278 and 717 modulate VLA-4 ligand binding and also contribute to alpha 4/180 formationPhysical state of the extracellular matrix regulates the structure and molecular composition of cell-matrix adhesionsMultivalent integrin-specific ligands enhance tissue healing and biomaterial integrationAnchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD proteinRho-stimulated contractility drives the formation of stress fibers and focal adhesionsCollagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrinsFocal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.Regulation of tenascin-C, a vascular smooth muscle cell survival factor that interacts with the alpha v beta 3 integrin to promote epidermal growth factor receptor phosphorylation and growthThe laminin-nidogen complex is a ligand for a specific splice isoform of the transmembrane protein tyrosine phosphatase LARIntegrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesisStructure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied ForcesTyrosine phosphorylation of paxillin and focal adhesion kinase by activation of muscarinic m3 receptors is dependent on integrin engagement by the extracellular matrixThe PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesionsInvolvement of focal adhesion kinase in invasin-mediated uptakeInteraction of focal adhesion kinase with cytoskeletal protein talinRegulation of cell adhesion by protein-tyrosine phosphatases. I. Cell-matrix adhesionThe role of conserved amino acid motifs within the integrin beta3 cytoplasmic domain in triggering focal adhesion kinase phosphorylationBinding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformationA role of tensin in skeletal-muscle regenerationSimulations of cell-surface integrin binding to nanoscale-clustered adhesion ligands.Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130CasA phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migrationProgressive kidney degeneration in mice lacking tensinp130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinaseIntegrin receptor activation triggers converging regulation of Cav1.2 calcium channels by c-Src and protein kinase A pathwaysExtracellular matrix and integrin signalling: the shape of things to come
P2860
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P2860
Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh-hant
name
Synergistic roles for receptor ...... tegrin transmembrane function.
@en
Synergistic roles for receptor ...... tegrin transmembrane function.
@nl
type
label
Synergistic roles for receptor ...... tegrin transmembrane function.
@en
Synergistic roles for receptor ...... tegrin transmembrane function.
@nl
prefLabel
Synergistic roles for receptor ...... tegrin transmembrane function.
@en
Synergistic roles for receptor ...... tegrin transmembrane function.
@nl
P2093
P2860
P356
P1433
P1476
Synergistic roles for receptor ...... tegrin transmembrane function.
@en
P2093
K M Yamada
S K Akiyama
S Miyamoto
P2860
P304
P356
10.1126/SCIENCE.7846531
P407
P577
1995-02-01T00:00:00Z