Localization of the gene for familial adenomatous polyposis on chromosome 5.
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The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phaseRibosomal protein genes are overexpressed in colorectal cancer: isolation of a cDNA clone encoding the human S3 ribosomal proteinActivation of the pp60c-src protein kinase is an early event in colonic carcinogenesisLoss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc geneA targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumorsReview of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramificationsIncrease in activity and level of pp60c-src in progressive stages of human colorectal cancerpp60c-src activation in human colon carcinomaDECIPHER: Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl ResourcesPhenotypic, cytogenetic, and molecular studies of three patients with constitutional deletions of chromosome 5 in the region of the gene for familial adenomatous polyposisHuman chromosome 5 complements the DNA double-strand break-repair deficiency and gamma-ray sensitivity of the XR-1 hamster variantTherapeutic upper gastrointestinal tract endoscopy in Paediatric GastroenterologyTargeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28EB/RP gene family encodes tubulin binding proteinsSecondary structure of an armadillo single repeat from the APC proteinThe novel oncogene CD24 and its arising role in the carcinogenesis of the GI tract: from research to therapySulindac and a cyclooxygenase-2 inhibitor, etodolac, increase APC mRNA in the colon of rats treated with azoxymethaneFunctional domains of axin. Importance of the C terminus as an oligomerization domainThe Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier systemColonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instabilityAge-specific incidence of cancer: Phases, transitions, and biological implicationsThe ninth Gordon Hamilton-Fairley memorial lecture. Hereditary cancers: clues to mechanisms of carcinogenesis.Recessive mechanisms of malignancy.Tumor-suppressor genes: cardinal factors in inherited predisposition to human cancersIdentification and regional localization of DNA markers on chromosome 7 for the cloning of the cystic fibrosis gene.Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas.Familial bone marrow monosomy 7. Evidence that the predisposing locus is not on the long arm of chromosome 7.Neurofibromatosis type 2 appears to be a genetically homogeneous disease.1989 Allen Award address: the American Society of Human Genetics annual meeting, Baltimore.Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells.Loss of alleles from the distal short arm of chromosome 1 occurs late in melanoma tumor progression.Skin fibroblasts from individuals hemizygous for the familial adenopolyposis susceptibility gene show delayed crisis in vitro.Distal deletion of chromosome Ip in ductal carcinoma of the breast.Aberrant crypt foci in colorectal carcinogenesis. Cell and crypt dynamics.Yeast artificial chromosomes for the molecular analysis of the familial polyposis APC gene region.Wireless capsule endoscopy in detecting small-intestinal polyps in familial adenomatous polyposis.Inheritance of human breast cancer: evidence for autosomal dominant transmission in high-risk families.Deletion of chromosome 5q and familial adenomatous polyposis.Obesity and abnormal behaviour associated with interstitial deletion of chromosome 18 (q12.2q21.1).A genetic linkage study of facioscapulohumeral (Landouzy-Déjérine) disease with 24 polymorphic DNA probes.
P2860
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P2860
Localization of the gene for familial adenomatous polyposis on chromosome 5.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh-hant
name
Localization of the gene for familial adenomatous polyposis on chromosome 5.
@en
Localization of the gene for familial adenomatous polyposis on chromosome 5.
@nl
type
label
Localization of the gene for familial adenomatous polyposis on chromosome 5.
@en
Localization of the gene for familial adenomatous polyposis on chromosome 5.
@nl
prefLabel
Localization of the gene for familial adenomatous polyposis on chromosome 5.
@en
Localization of the gene for familial adenomatous polyposis on chromosome 5.
@nl
P2093
P356
P1433
P1476
Localization of the gene for familial adenomatous polyposis on chromosome 5.
@en
P2093
Lucibello FC
Scambler P
P2888
P304
P356
10.1038/328614A0
P407
P577
1987-08-01T00:00:00Z
P6179
1049552358