X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt(NH3)2(d(pGpG))]
about
Isolation of cDNAs encoding a human protein that binds selectively to DNA modified by the anticancer drug cis-diamminedichloroplatinum(II)Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplexChiral discrimination in platinum anticancer drugs.Crystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: hydration at the platinated siteHMG-D complexed to a bulge DNA: An NMR modelCrystal Structures of Cisplatin Bound to a Human Copper ChaperoneStructural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4"Post-it" type connected DNA created with a reversible covalent cross-linkRad5 template switch pathway of DNA damage tolerance determines synergism between cisplatin and NSC109268 in Saccharomyces cerevisiaeDisturbance of DNA conformation by the binding of testosterone-based platinum drugs via groove-face and intercalative interactions: a molecular dynamics simulation study.Study of the interaction of DNA with cisplatin and other Pd(II) and Pt(II) complexes by atomic force microscopy.Gas-phase ion/ion reactions of transition metal complex cations with multiply charged oligodeoxynucleotide anions.Thymine dimers bend DNA.The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove.Binding of kinetically inert metal ions to RNA: the case of platinum(II).NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner.Unusual DNA binding modes for metal anticancer complexes.Cellular responses to Cisplatin-induced DNA damage.Applications of synchrotron-based spectroscopic techniques in studying nucleic acids and nucleic acid-functionalized nanomaterialsThird row transition metals for the treatment of cancerSynthesis, characterization and biological activity of trans-platinum(II) complexes with chloroquine.Sensitive Marker of the Cisplatin-DNA Interaction: X-Ray Photoelectron Spectroscopy of CL.Treatment with inhibitors of polyamine biosynthesis, which selectively lower intracellular spermine, does not affect the activity of alkylating agents but antagonizes the cytotoxicity of DNA topoisomerase II inhibitors.Nucleotide excision repair in Escherichia coliEngineering terminal disulfide bonds into DNA.Inhibition of transcription by platinum antitumor compoundsInteraction of classical platinum agents with the monomeric and dimeric Atox1 proteins: a molecular dynamics simulation study.Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs.Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies.Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid.Oligonucleotide structure: a decade of results from single crystal X-ray diffraction studies.[Pt(O,O'-acac)(γ-acac)(DMS)] versus cisplatin: apoptotic effects in B50 neuroblastoma cells.The effect of potential supramolecular-bond promoters on the DNA-interacting abilities of copper-terpyridine compounds.A cytotoxic and cytostatic gold(III) corrole."Head-to-head" double-hamburger-like structure of di-ruthenated d(GpG) adducts of mono-functional Ru-arene anticancer complexes.Atomic level rendering of DNA-drug encounter.Mutational analysis of the DNA binding domain A of chromosomal protein HMG1.Chiral differentiation of DNA adducts formed by enantiomeric analogues of antitumor cisplatin is sequence-dependent.Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line.Bifunctional binding of cisplatin to DNA: why does cisplatin form 1,2-intrastrand cross-links with ag but not with GA?
P2860
Q24604428-58AF9112-B3A6-462E-A293-A1C2103A21DAQ24622867-0E3F95BA-766E-492B-8C03-601FF2E9434FQ24812493-9A629AD8-7F68-4755-B04B-948CC459CCE2Q27617786-26B704D3-2857-44A1-AFCD-B2CC987893E6Q27631688-174E1472-4B51-4F38-B47B-8135A4D135FAQ27657700-8B1C43A1-CBFB-43C1-8F50-89A0C6340E40Q27662057-D4906313-EF91-4841-BBE9-7C28F32DF2F5Q27696245-56FED708-FE7C-44DA-9DEF-72E78EB0168CQ28534339-A3CE8BC6-C9B5-41DC-B134-EE6E9210EC20Q30538107-D7CFE758-015F-4E87-9CED-296A2907BB0DQ32103947-1C901479-22EF-497C-99B7-B290A222790EQ33310555-58199606-4425-4B77-9550-E380F52D91C6Q33567081-E62C73D9-6C22-4F71-8A05-4D861F2FBCA7Q33580129-13CA0886-FB36-4398-9E1C-FCEB82F82A68Q33842478-5106D7FC-1D11-43A1-A2A7-308276BA55C3Q33930946-FF083541-6218-45DB-92FC-77558C3D48F4Q34071185-84881B88-383C-4DD9-A4A1-68EBCBEC3B4FQ34089685-70DB62EC-7676-4DFB-94C7-8BA2757AA697Q34766893-C2D387D6-A67A-44AA-BC7F-937AF1CF16E3Q35128394-D38CB25D-936B-4DC8-8EA4-BCE53F196178Q35803993-10C3A231-7441-4F80-894C-6AFD8CF2370CQ36362182-92B2F388-FCDA-4BF3-98BA-A90C87CF5E7FQ36420098-29F316CB-B3E0-4119-BEA0-25394C02BAEDQ37056044-90AF52CE-E82A-4706-9CB9-5DCA468DF488Q37144674-33B0A8C0-9645-4E16-B727-8A486467BDE7Q37364815-DF40E5C5-D266-4D80-8076-488E821DAAADQ37535399-87B030FF-2884-401D-A888-CEF75266007DQ37603642-003EAE82-564A-4D9E-8231-2431C02C10BAQ37729428-6F6101B8-B54D-4C57-A8BD-B314E8EB4F41Q37746856-A685DB02-0911-4894-B50E-EFA59512A312Q38767028-6D302269-619F-48CC-A119-475332EEA4D8Q38805298-9058E22B-823E-4786-A617-8E0EC9F7518EQ38842569-5A6B5249-C495-475F-9B4B-0761580ABB1AQ38953691-D4E3BC4A-5AF5-476F-9007-07669A368A08Q39199644-41CBD209-E3FF-4941-85D1-897C3FBFA7D8Q39264801-F341A8BB-63E5-4644-A090-410143397667Q40224937-2A6755CC-60E7-4D2D-A098-6C2760B5E427Q40335117-8038DF8D-E88C-4FCC-A85F-4A134B5102A4Q40921673-DBEE5330-1355-4039-90B0-CD4401F98FDEQ41258864-7956F33B-9C2E-48D8-99FB-FFFC99A40B77
P2860
X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt(NH3)2(d(pGpG))]
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh-hant
name
X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt
@nl
X-ray structure of the major a ...... h DNA: cis-[Pt(NH3)2(d(pGpG))]
@en
type
label
X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt
@nl
X-ray structure of the major a ...... h DNA: cis-[Pt(NH3)2(d(pGpG))]
@en
prefLabel
X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt
@nl
X-ray structure of the major a ...... h DNA: cis-[Pt(NH3)2(d(pGpG))]
@en
P2093
P356
P1433
P1476
X-ray structure of the major a ...... h DNA: cis-[Pt(NH3)2(d(pGpG))]
@en
P2093
P304
P356
10.1126/SCIENCE.4048939
P407
P577
1985-10-01T00:00:00Z