Unsaturated fatty acids stimulate NADPH-dependent superoxide production by cell-free system derived from macrophages.
about
Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidaseCharacterization of the 47-kilodalton autosomal chronic granulomatous disease protein: tissue-specific expression and transcriptional control by retinoic acidDetection of superoxide anion and hydrogen peroxide production by cellular NADPH oxidasesTripartite chimeras comprising functional domains derived from the cytosolic NADPH oxidase components p47phox, p67phox, and Rac1 elicit activator-independent superoxide production by phagocyte membranes: an essential role for anionic membrane phosphArachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase.Mapping of functional domains in p47(phox) involved in the activation of NADPH oxidase by "peptide walking".SH3-dependent assembly of the phagocyte NADPH oxidase.The Voltage-Gated Proton Channel: A Riddle, Wrapped in a Mystery, inside an Enigma.A regulated adaptor function of p40phox: distinct p67phox membrane targeting by p40phox and by p47phox.Superoxide production in Galleria mellonella hemocytes: identification of proteins homologous to the NADPH oxidase complex of human neutrophilsCytosolic components of the respiratory burst oxidase: resolution of four components, two of which are missing in complementing types of chronic granulomatous diseaseA prenylated p47phox-p67phox-Rac1 chimera is a Quintessential NADPH oxidase activator: membrane association and functional capacity.Arachidonic acid induces direct interaction of the p67(phox)-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production.The p67-phox cytosolic peptide of the respiratory burst oxidase from human neutrophils. Functional aspectsRequirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase.Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agonists. Differential effects of a novel protein kinase inhibitor.Activation of the human neutrophil nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase by protein kinase CActivation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system.Modulation of the alveolar macrophage superoxide production by protein phosphorylation.Electron and proton transport by NADPH oxidasesTwo CGD Families with a Hypomorphic Mutation in the Activation Domain of p67(phox)Coregulation of NADPH oxidase activation and phosphorylation of a 48-kD protein(s) by a cytosolic factor defective in autosomal recessive chronic granulomatous disease.The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems.Can essential fatty acids reduce the burden of disease(s)?Kinetic characterization of the redox components in solubilized membranes from porcine neutrophils: reduction with dithionite and photoexcited NAD(P)H.Reactive oxygen species in phagocytic leukocytesRegulation of Nox and Duox enzymatic activity and expressionBiological roles for the NOX family NADPH oxidases.O2- production by B lymphocytes lacking the respiratory burst oxidase subunit p47phox after transfection with an expression vector containing a p47phox cDNA.Regulation of NADPH oxidase activity by Rac GTPase activating protein(s).Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task.The intimate and controversial relationship between voltage-gated proton channels and the phagocyte NADPH oxidase.Constitutive NADPH-dependent electron transferase activity of the Nox4 dehydrogenase domain.The cytosolic subunit p67phox contains an NADPH-binding site that participates in catalysis by the leukocyte NADPH oxidase.Functional defect in neutrophil cytosols from two patients with autosomal recessive cytochrome-positive chronic granulomatous disease.Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor.Role of nucleotides and phosphoinositides in the stability of electron and proton currents associated with the phagocytic NADPH oxidase.Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP.Arachidonic acid release is closely related to the Fc gamma receptor-mediated superoxide generation in macrophages.Activation of the leukocyte NADPH oxidase by protein kinase C in a partially recombinant cell-free system.
P2860
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P2860
Unsaturated fatty acids stimulate NADPH-dependent superoxide production by cell-free system derived from macrophages.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
@wuu
1984年学术文章
@zh
1984年学术文章
@zh-cn
1984年学术文章
@zh-hans
1984年学术文章
@zh-my
1984年学术文章
@zh-sg
1984年學術文章
@yue
1984年學術文章
@zh-hant
name
Unsaturated fatty acids stimul ...... stem derived from macrophages.
@en
Unsaturated fatty acids stimul ...... stem derived from macrophages.
@nl
type
label
Unsaturated fatty acids stimul ...... stem derived from macrophages.
@en
Unsaturated fatty acids stimul ...... stem derived from macrophages.
@nl
prefLabel
Unsaturated fatty acids stimul ...... stem derived from macrophages.
@en
Unsaturated fatty acids stimul ...... stem derived from macrophages.
@nl
P1433
P1476
Unsaturated fatty acids stimul ...... stem derived from macrophages.
@en
P2093
P304
P356
10.1016/0008-8749(84)90066-2
P577
1984-10-01T00:00:00Z